Evidence map›Paper›PMID 25623474›Full record

ArticleCurrent treatment options in gastroenterology2015

Sessile serrated polyps: detection, eradication, and prevention of the evil twin.

Joshua C Obuch, Courtney M Pigott, Dennis J Ahnen

Abstract read
In one paragraph

Article in Current treatment options in gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Review
  5. Article
  6. Early Onset Colorectal Cancer: Molecular Underpinnings Accelerating Occurrence.Cellular and molecular gastroenterology and hepatology · 2025
    Review
  7. Article
  8. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joshua C ObuchDepartment of Medicine, Division of Gastroenterology, University of Colorado School of Medicine, Denver, CO, USA.
Courtney M Pigott
Dennis J Ahnen

Funding

Colorectal Chemoprevention with Calcium and Vitamin DR01CA098286 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARON, JOHN ANTHONY · 2003 to 2015
$43.9M
FOLATE, DNA METHYLATION AND CARCINOGENESIS IN THE BOWELR01CA059005 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARON, JOHN ANTHONY · 1993 to 2013
$17.3M
GASTROINTESTINAL DISEASE TRAINING GRANTT32DK007038 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 1986 to 2020
$3.5M
NCI NIH HHS R01 CA059005NCI NIH HHS R01 CA098286NIDDK NIH HHS T32 DK007038
6 · The paper itself

Abstract

opinion statementThe sessile serrated polyp (SSP), also known as sessile serrated adenoma, is the evil twin among the colorectal cancer precursors. As will be described, these lesions have multiple aliases (serrated adenoma, serrated polyp, or serrated lesion among others), they hang out in a bad neighborhood (the poorly prepped right colon), they hide behind a mask of mucus, they are difficult for witnesses (pathologists) to identify, they are difficult for police (endoscopists) to find, they are difficult to permanently remove from the society (high incomplete resection rate), they can be impulsive (progress rapidly to colorectal cancer (CRC)), and enforcers (gastroenterologists) do not know how best to control them (uncertain surveillance recommendations). There is no wonder that there is a need to understand these lesions well, learn how best to prevent the colonic mucosa from going down this errant path or, if that fails, detect these deviants and eradicate them from the colonic society. These lesions should be on endoscopists' most wanted list.

Identifiers

PMID25623474
PMCPMC4427517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.