ArticleeLife2015
Learning the specific quality of taste reinforcement in larval Drosophila.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 68 citations in OpenAlex.
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- Selective octopaminergic tuning of mushroom body circuits during memory formation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Finding a path: local search behavior of Drosophila larvae.The Journal of experimental biology · 2025Article
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- Cognitive limits of larvalLearning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- IR76b-expressing neurons inBiology letters · 2024Article
- Prediction error drives associative learning and conditioned behavior in a spiking model of Drosophila larva.iScience · 2024Article
- Rewarding Capacity of Optogenetically Activating a Giant GABAergic Central-Brain Interneuron in LarvalThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Ethanol-guided behavior in Drosophila larvae.Scientific reports · 2021Article
- To be specific: The role of orbitofrontal cortex in signaling reward identity.Behavioral neuroscience · 2021Review
- Identification of Dopaminergic Neurons That Can Both Establish Associative Memory and Acutely Terminate Its Behavioral Expression.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Reversal learning inLearning & memory (Cold Spring Harbor, N.Y.) · 2019Article
- Reward signaling in a recurrent circuit of dopaminergic neurons and peptidergic Kenyon cells.Nature communications · 2019Article
- One-trial learning in larvalLearning & memory (Cold Spring Harbor, N.Y.) · 2019Article
- Article
- Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila.Nature communications · 2018Article
- Associative Learning of Stimuli Paired and Unpaired With Reinforcement: Evaluating Evidence From Maggots, Flies, Bees, and Rats.Frontiers in psychology · 2018Article
- Article
- Common microbehavioral "footprint" of two distinct classes of conditioned aversion.Learning & memory (Cold Spring Harbor, N.Y.) · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The only property of reinforcement insects are commonly thought to learn about is its value. We show that larval Drosophila not only remember the value of reinforcement (How much?), but also its quality (What?). This is demonstrated both within the appetitive domain by using sugar vs amino acid as different reward qualities, and within the aversive domain by using bitter vs high-concentration salt as different qualities of punishment. From the available literature, such nuanced memories for the quality of reinforcement are unexpected and pose a challenge to present models of how insect memory is organized. Given that animals as simple as larval Drosophila, endowed with but 10,000 neurons, operate with both reinforcement value and quality, we suggest that both are fundamental aspects of mnemonic processing-in any brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.