Evidence map›Paper›PMID 25621705›Full record

ArticleNucleosides, nucleotides & nucleic acids2015

Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites.

Jun Lu, Selene C Koo, Nan-Sheng Li, Joseph A Piccirilli

Abstract read
In one paragraph

Article in Nucleosides, nucleotides & nucleic acids, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. RNA Control via Redox-Responsive Acylation.Angewandte Chemie (International ed. in English) · 2024
    Article
  2. Synthesis of Oligoribonucleotides Containing a 2'-Amino-5'-The Journal of organic chemistry · 2021
    Article
  3. Review
  4. RNA Control by Photoreversible Acylation.Journal of the American Chemical Society · 2018
    Article
  5. Synthesis of 5'-Thio-3'-O-ribonucleoside Phosphoramidites.The Journal of organic chemistry · 2017
    Article
  6. Photo-controlled cell-specific metabolic labeling of RNA.Organic & biomolecular chemistry · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun Lua Department of Biochemistry & Molecular Biology and Department of Chemistry , University of Chicago , Chicago , Illinois , United States.
Selene C Koo
Nan-Sheng Li
Joseph A Piccirilli

Funding

The Catalytic Mechanism of Nuclear Premessenger RNA Splicing by the SpliceosomeR01GM088656 · NIGMS · UNIVERSITY OF CHICAGO · PI PICCIRILLI, JOSEPH ANTHONY, STALEY, JONATHAN P · 2010 to 2017
$4.2M
Investigating the Catalytic Mechanism of the HDV RibozymeR01AI081987 · NIAID · UNIVERSITY OF CHICAGO · PI PICCIRILLI, JOSEPH ANTHONY · 2010 to 2014
$1.8M
NIAID NIH HHS 1R01-AI081987NIAID NIH HHS R01 AI081987NIGMS NIH HHS R01 GM088656
6 · The paper itself

Abstract

The chemical synthesis and incorporation of the phosphoramidite derivatives of 2 '-O-photocaged ribonucleosides (A, C, G and U) with o-nitrobenzyl, α-methyl-o-nitrobenzyl or 4,5-dimethoxy-2-nitrobenzyl group into oligoribonucleotides are described. The efficiency of UV irradiated uncaging of these 2'-O-photocaged oligoribonucleotides was found in the order of α-methyl-o-nitrobenzyl < 4,5-dimethoxy-2-nitrobenzyl < 2'-O-o-nitrobenzyl.

Indexed as

Hydrogen-Ion ConcentrationOligonucleotidesOrganophosphorus CompoundsPhotochemistryRibonucleosidesRNATemperatureUltraviolet RaysOligonucleotidesOrganophosphorus CompoundsphosphoramiditeRibonucleosidesRNA2′-O-4,5-dimethoxy-2-nitrobenzyl.2′-O-o-nitrobenzyl2′-O-photocaged oligomers2′-O-photocaged phosphoramdites2′-O-photocaged ribonucleosides2′-O-α-methyl-o-nitrobenzyl

Identifiers

PMID25621705
PMCPMC6461471

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.