Evidence map›Paper›PMID 25621207›Full record

ReviewWorld journal of orthopedics2015

Acute complications of spinal cord injuries.

Ellen Merete Hagen

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of orthopedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06333886 (Using a Point-of-care Electrophysiological Method to Study the Impact of Neuro-sacral Function on Recovery After Acute Spinal Cord Injuries), which is not on this map. Cited by 96 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 8 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06333886 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Using a Point-of-care Electrophysiological Method to Study the Impact of Neuro-sacral Function on Recovery After Acute Spinal Cord Injuries

TypeobservationalSponsorCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealRan2024 to 2028Enrolled450ConditionsSpinal Cord Injuries, Neurogenic Bowel, Neurogenic Bladder DysfunctionArmsSacral electromyography
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 8 syntheses or guidelines pooled it, 221 citations in OpenAlex.

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  6. Alginate scaffolds improve functional recovery after spinal cord injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Pooled it
  7. A review of spinal cord perfusion pressure guided interventions in traumatic spinal cord injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  8. Pooled it
  9. Injury and therapy in a human spinal cord organoid.Nature biomedical engineering · 2026
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ellen Merete HagenEllen Merete Hagen, Spinal Cord Injury Centre of Western Denmark, Department of Neurology, Regional Hospital of Viborg, 8800 Viborg, Denmark.
Regionshospitalet Viborg · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this paper is to give an overview of acute complications of spinal cord injury (SCI). Along with motor and sensory deficits, instabilities of the cardiovascular, thermoregulatory and broncho-pulmonary system are common after a SCI. Disturbances of the urinary and gastrointestinal systems are typical as well as sexual dysfunction. Frequent complications of cervical and high thoracic SCI are neurogenic shock, bradyarrhythmias, hypotension, ectopic beats, abnormal temperature control and disturbance of sweating, vasodilatation and autonomic dysreflexia. Autonomic dysreflexia is an abrupt, uncontrolled sympathetic response, elicited by stimuli below the level of injury. The symptoms may be mild like skin rash or slight headache, but can cause severe hypertension, cerebral haemorrhage and death. All personnel caring for the patient should be able to recognize the symptoms and be able to intervene promptly. Disturbance of respiratory function are frequent in tetraplegia and a primary cause of both short and long-term morbidity and mortality is pulmonary complications. Due to physical inactivity and altered haemostasis, patients with SCI have a higher risk of venous thromboembolism and pressure ulcers. Spasticity and pain are frequent complications which need to be addressed. The psychological stress associated with SCI may lead to anxiety and depression. Knowledge of possible complications during the acute phase is important because they may be life threatening and/ or may lead to prolonged rehabilitation.

Indexed as

Autonomic dysreflexiaBradycardiaCardiovascular diseaseOrthostatic hypotensionRespiratory insufficiencySpinal cord injuriesThromboembolism

Identifiers

PMID25621207
PMCPMC4303786
OpenAlexW2077453160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.