Evidence map›Paper›PMID 25621119›Full record

ReviewWorld journal of stem cells2015

Stem cells for spine surgery.

Joshua Schroeder, Janina Kueper, Kaplan Leon, Meir Liebergall

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 36 citations in OpenAlex.

  1. Bone Growth Stimulators to Enhance Spinal Fusion Outcomes.Spine surgery and related research · 2026
    Review
  2. Review
  3. Review
  4. Review
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  6. Review
  7. Current Concepts of Stem Cell Therapy for Chronic Spinal Cord Injury.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joshua SchroederJoshua Schroeder, Kaplan Leon, Meir Liebergall, Department of Orthopedic Surgery, Spine Surgery, Hadassah Medical Center, Kiryat Hadassah, Jerusalem 91120, Israel.
Janina KueperJoshua Schroeder, Kaplan Leon, Meir Liebergall, Department of Orthopedic Surgery, Spine Surgery, Hadassah Medical Center, Kiryat Hadassah, Jerusalem 91120, Israel.
Kaplan LeonJoshua Schroeder, Kaplan Leon, Meir Liebergall, Department of Orthopedic Surgery, Spine Surgery, Hadassah Medical Center, Kiryat Hadassah, Jerusalem 91120, Israel.
Meir LiebergallJoshua Schroeder, Kaplan Leon, Meir Liebergall, Department of Orthopedic Surgery, Spine Surgery, Hadassah Medical Center, Kiryat Hadassah, Jerusalem 91120, Israel.
Hadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past few years, stem cells have become the focus of research by regenerative medicine professionals and tissue engineers. Embryonic stem cells, although capable of differentiating into cell lineages of all three germ layers, are limited in their utilization due to ethical issues. In contrast, the autologous harvest and subsequent transplantation of adult stem cells from bone marrow, adipose tissue or blood have been experimentally utilized in the treatment of a wide variety of diseases ranging from myocardial infarction to Alzheimer's disease. The physiologic consequences of stem cell transplantation and its impact on functional recovery have been studied in countless animal models and select clinical trials. Unfortunately, the bench to bedside translation of this research has been slow. Nonetheless, stem cell therapy has received the attention of spinal surgeons due to its potential benefits in the treatment of neural damage, muscle trauma, disk degeneration and its potential contribution to bone fusion.

Indexed as

FusionIntervertebral disk regenerationPeripheral nerve damageSkeletal muscle regenerationSpinal cord injurySpine surgeryStem cell

Identifiers

PMID25621119
PMCPMC4300930
OpenAlexW2089072209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.