Evidence map›Paper›PMID 25621028›Full record

ArticleOncology letters2015

Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer.

Guo-Qiang Su, Fu-Xing Zhang, He-Hui Mao, Xian-Wei Liu, Yong-Sheng Zheng, Si-Yu Zhang, Jing-Jun Su

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Guo-Qiang SuDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
Fu-Xing ZhangDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
He-Hui MaoDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
Xian-Wei LiuDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
Yong-Sheng ZhengDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
Si-Yu ZhangDepartment of General Surgery, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
Jing-Jun SuDepartment of Ultrasound Diagnosis, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian 361003, P.R. China.
First Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is the fourth most common type of malignant tumor, with a poor prognosis. Focal adhesion kinase (FAK) mediates the crosslink of intracellular signaling networks, playing a key role in cell migration and invasion. The aim of the present study was to investigate the effects of FAK interference on the proliferation ability, invasion and metastasis of gastric cancer cells. The FAK-RNAi lentiviral vector was infected into SGC7901 gastric cancer cells in order to observe the

Indexed as

focal adhesion kinasegastric cancerinvasionmetastasisnude mouseRNAi

Identifiers

PMID25621028
PMCPMC4301487
OpenAlexW2014573649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.