Evidence map›Paper›PMID 25621014›Full record

ArticleGenome medicine2014

Single cell genomics of bacterial pathogens: outlook for infectious disease research.

Jeffrey S McLean, Roger S Lasken

Abstract read
In one paragraph

Article in Genome medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Chlamydiae - What's New?Journal of veterinary research · 2020
    Article
  4. Review
  5. Viable bacteria persist on antibiotic spacers following two-stage revision for periprosthetic joint infection.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeffrey S McLeanSchool of Dentistry, Department of Periodontics, University of Washington, Seattle, WA 98195 USA ; J. Craig Venter Institute, Capricorn Lane, La Jolla, CA 92037 USA.
Roger S LaskenJ. Craig Venter Institute, Capricorn Lane, La Jolla, CA 92037 USA.

Funding

Domestication and characterization of TM7-the most elusive oral phylumR01DE023810 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xuesong He, Jeffrey Scott McLean · 2014 to 2026
$6.6M
Making a quantum leap in plaque research with modern sciencesR01DE020102 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HE, XUESONG, MCLEAN, JEFFREY SCOTT · 2010 to 2020
$3.7M
WHOLE GENOME AMPLIFICATION FOR RAPID LOW COST GENOTYPINGR01HG003647 · NHGRI · J. CRAIG VENTER INSTITUTE, INC. · PI LASKEN, ROGER SENDER · 2005 to 2013
$3.6M
Moving Beyond Diversity by Revealing Biological Functions of Uncultured BacteriaR01GM095373 · NIGMS · J. CRAIG VENTER INSTITUTE, INC. · PI MCLEAN, JEFFREY SCOTT, YOOSEPH, SHIBU · 2011 to 2014
$1.7M
NHGRI NIH HHS R01 HG003647NIAID NIH HHS HHSN272200900007CNIDCR NIH HHS R01 DE020102NIDCR NIH HHS R01 DE023810NIGMS NIH HHS R01 GM095373
6 · The paper itself

Abstract

Genomic sequencing from single cells is a powerful tool in microbiology and holds great promise for infectious disease research. Vast numbers of uncultivable species and pathogens that persist at low abundance in environmental reservoirs are now accessible for genomic analysis.

Identifiers

PMID25621014
PMCPMC4304388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.