Evidence map›Paper›PMID 25620930›Full record

ArticleFrontiers in aging neuroscience2014

Consolidation in older adults depends upon competition between resting-state networks.

Heidi I L Jacobs, Kim N H Dillen, Okka Risius, Yasemin Göreci, Oezguer A Onur, Gereon R Fink, Juraj Kukolja

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Dopaminergic mechanisms supporting hippocampal postencoding dynamics in humans.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. A Multivariate Assessment of Age-Related Cognitive Impairment inFrontiers in integrative neuroscience · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Heidi I L JacobsCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany.
Kim N H DillenCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany.
Okka RisiusCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany.
Yasemin GöreciDepartment of Neurology, University Hospital of Cologne Cologne, Germany.
Oezguer A OnurCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany ; Department of Neurology, University Hospital of Cologne Cologne, Germany.
Gereon R FinkCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany ; Department of Neurology, University Hospital of Cologne Cologne, Germany.
Juraj KukoljaCognitive Neuroscience, Research Centre Jülich, Institute of Neuroscience and Medicine (INM3) Jülich, Germany ; Department of Neurology, University Hospital of Cologne Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory encoding and retrieval problems are inherent to aging. To date, however, the effect of aging upon the neural correlates of forming memory traces remains poorly understood. Resting-state fMRI connectivity can be used to investigate initial consolidation. We compared within and between network connectivity differences between healthy young and older participants before encoding, after encoding and before retrieval by means of resting-state fMRI. Alterations over time in the between-network connectivity analyses correlated with retrieval performance, whereas within-network connectivity did not: a higher level of negative coupling or competition between the default mode and the executive networks during the after encoding condition was associated with increased retrieval performance in the older adults, but not in the young group. Data suggest that the effective formation of memory traces depends on an age-dependent, dynamic reorganization of the interaction between multiple, large-scale functional networks. Our findings demonstrate that a cross-network based approach can further the understanding of the neural underpinnings of aging-associated memory decline.

Indexed as

agingcompensationcompetitionconsolidationfMRImemorynetworksresting-state

Identifiers

PMID25620930
PMCPMC4288239

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.