Evidence map›Paper›PMID 25620902›Full record

ArticleLaser physics letters2014

3D-resolved targeting of photodynamic therapy using temporal focusing.

Christopher J Rowlands, Jackie Wu, Sebastien G M Uzel, Oliver Klein, Conor L Evans, Peter T C So

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laser physics letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher J RowlandsDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Jackie WuDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Sebastien G M UzelDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Oliver KleinWellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Conor L EvansWellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Peter T C SoDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA ; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
Imaging and Overcoming Hypoxia-Induced Resistance in Metastatic Ovarian CancerDP2OD007096 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI EVANS, CONOR LEE · 2010 to 2010
$2.7M
Regenerative Healing Using ECM Based ScaffoldsR01NS051320 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YANNAS, IOANNIS V · 2006 to 2009
$1.6M
High Throughput Manufacturing for Three-Dimensional Microfluidic DevicesR44EB012415 · NIBIB · FEMTOFAB, INC. · PI JANG, YUN-HO · 2011 to 2013
$849k
NIBIB NIH HHS P41 EB015871NIBIB NIH HHS R44 EB012415NIH HHS DP2 OD007096NINDS NIH HHS R01 NS051320Wellcome Trust
6 · The paper itself

Abstract

A method for selectively inducing apoptosis in tumor nodules is presented, with close-to-cellular level resolution, using 3D-resolved widefield temporal focusing illumination. Treatment times on the order of seconds were achieved using Verteporfin as the photosensitizer, with doses of 30

Indexed as

cancerphotodynamic therapytemporal focusingultrafast amplifier

Identifiers

PMID25620902
PMCPMC4301304

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.