ArticleJournal of applied econometrics (Chichester, England)
ESTIMATING PERSON-CENTERED TREATMENT (PeT) EFFECTS USING INSTRUMENTAL VARIABLES: AN APPLICATION TO EVALUATING PROSTATE CANCER TREATMENTS.
Article in Journal of applied econometrics (Chichester, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Applying methods for personalized medicine to the treatment of alcohol use disorder.Journal of consulting and clinical psychology · 2021Trial
- PERsonalised Medicine for Intensification of Treatment (PERMIT) in type 2 diabetes mellitus: a target trial emulation from routine data.Health technology assessment (Winchester, England) · 2026Article
- Comparative effectiveness of alternative second-line oral glucose-lowering therapies for type 2 diabetes: a precision medicine approach applied to routine data.Diabetologia · 2025Article
- Going beyond randomised controlled trials to assess treatment effect heterogeneity across target populations.Health economics · 2025Article
- An Approach for Combining Clinical Judgment with Machine Learning to Inform Medical Decision Making: Analysis of Nonemergency Surgery Strategies for Acute Appendicitis in Patients with Multiple Long-Term Conditions.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- Machine Learning Methods to Estimate Individualized Treatment Effects for Use in Health Technology Assessment.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Review
- How does a local instrumental variable method perform across settings with instruments of differing strengths? A simulation study and an evaluation of emergency surgery.Health economics · 2023Article
- DAta Linkage to Enhance Cancer Care (DaLECC): Protocol of a Large Australian Data Linkage Study.International journal of environmental research and public health · 2023Article
- Local Instrumental Variable Methods to Address Confounding and Heterogeneity when Using Electronic Health Records: An Application to Emergency Surgery.Medical decision making : an international journal of the Society for Medical Decision Making · 2022Article
- A Machine-Learning Approach for Estimating Subgroup- and Individual-Level Treatment Effects: An Illustration Using the 65 Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2022Article
- Remission and Relapse of Dyslipidemia After Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass in a Racially and Ethnically Diverse Population.JAMA network open · 2022Article
- Effectiveness of emergency surgery for five common acute conditions: an instrumental variable analysis of a national routine database.Anaesthesia · 2022Article
- Comparative effectiveness of gastric bypass and sleeve gastrectomy on predicted 10-year risk of cardiovascular disease 5 years after surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- A likely responder approach for the analysis of randomized controlled trials.Contemporary clinical trials · 2022Article
- Observational
- Article
- Comparative Effectiveness of Gastric Bypass and Vertical Sleeve Gastrectomy for Hypertension Remission and Relapse: The ENGAGE CVD Study.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Optimal individualized decision rules using instrumental variable methods.Journal of the American Statistical Association · 2021Article
- Effectiveness of Gastric Bypass Versus Gastric Sleeve for Cardiovascular Disease: Protocol and Baseline Results for a Comparative Effectiveness Study.JMIR research protocols · 2020Article
- Imprecise Data and Their Impact on Translational Research in Medicine.Frontiers in medicine · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
This paper builds on the methods of local instrumental variables developed by Heckman and Vytlacil (1999, 2001, 2005) to estimate person-centered treatment (PeT) effects that are conditioned on the person's observed characteristics and averaged over the potential conditional distribution of unobserved characteristics that lead them to their observed treatment choices. PeT effects are more individualized than conditional treatment effects from a randomized setting with the same observed characteristics. PeT effects can be easily aggregated to construct any of the mean treatment effect parameters and, more importantly, are well suited to comprehend individual-level treatment effect heterogeneity. The paper presents the theory behind PeT effects, and applies it to study the variation in individual-level comparative effects of prostate cancer treatments on overall survival and costs.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.