Evidence map›Paper›PMID 25620732›Full record

ArticleDrug and alcohol dependence2015

Challenges to implementing opioid substitution therapy in Ukrainian prisons: Personnel attitudes toward addiction, treatment, and people with HIV/AIDS.

Maxim Polonsky, Lyuba Azbel, Jeffrey A Wickersham, Faye S Taxman, Evgeny Grishaev, Sergey Dvoryak, Frederick L Altice

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maxim PolonskyYale University School of Medicine, Section of Infectious Diseases, New Haven, CT, USA; Ukrainian Institute on Public Health Policy, Kiev, Ukraine. Electronic address: maxim.polonsky@yale.edu.
Lyuba AzbelYale University School of Medicine, Section of Infectious Diseases, New Haven, CT, USA; Ukrainian Institute on Public Health Policy, Kiev, Ukraine.
Jeffrey A WickershamYale University School of Medicine, Section of Infectious Diseases, New Haven, CT, USA.
Faye S TaxmanGeorge Mason University, Fairfax, VA, USA.
Evgeny GrishaevUkrainian Institute on Public Health Policy, Kiev, Ukraine.
Sergey DvoryakUkrainian Institute on Public Health Policy, Kiev, Ukraine.
Frederick L AlticeYale University School of Medicine, Section of Infectious Diseases, New Haven, CT, USA; Yale University School of Public Health, Division of Epidemiology of Microbial Diseases, New Haven, CT, USA.
Ukrainian Institute of Public Health Policy · UAGeorge Mason University · USYale University · US

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Prison Interventions and HIV Prevention CollaborationR01DA029910 · NIDA · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE · 2010 to 2026
$7.9M
Expanding Medication Assisted Therapy in Ukraine (ExMAT)R01DA033679 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2012 to 2021
$6.4M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
Training in Drug Abuse & HIV Prevention for Female & Transgender Sex WorkersK01DA038529 · NIDA · YALE UNIVERSITY · PI WICKERSHAM, JEFFREY ALLEN · 2014 to 2018
$838k
FIC NIH HHS D43 TW010540FIC NIH HHS R25 TW009338NIDA NIH HHS K01 DA038529NIDA NIH HHS K24 DA017072NIDA NIH HHS R01 DA029910NIDA NIH HHS R01 DA033679
6 · The paper itself

Abstract

backgroundUkraine is experiencing one of the most volatile HIV epidemics globally, fueled primarily by people who inject drugs (PWIDs), and a parallel incarceration epidemic. Opioid substitution therapy (OST) is internationally recognized as one of the most effective forms of treatment for opioid dependence and is among the most effective HIV prevention strategies available, yet efforts to adopt it in Ukraine's Criminal Justice System (CJS) have been thwarted.

methodsTo understand the reluctance of the Ukrainian CJS to adopt OST despite the overwhelming evidence pointing to its health benefits and improved criminal justice outcomes, we conducted the first survey of Ukrainian prison administrative, medical and custodial staff (N=243) attitudes towards addiction in general, OST, and people living with HIV/AIDS (PLWHA) in representative regions of Ukraine.

resultsResults revealed that Ukrainian CJS workers' attitudes toward OST, PLWHA, and drug addiction were universally negative, but differed substantially along geographic and occupational lines. Whereas geographic and cultural proximity to the European Union drove positive attitudes in the west, in the southern region we observed an identifiability effect, as workers who worked directly with prisoners held the most positive attitudes. We also found that knowledge mediated the effect of drug intolerance on OST attitudes.

conclusionIn Ukraine, adoption of OST is more influenced by myths, biases and ideological prejudices than by existing scientific evidence. By elucidating existing attitudes among CJS personnel, this study will help to direct subsequent interventions to address the barriers to implementing evidence-based HIV prevention treatments.

Indexed as

Attitude of Health PersonnelAcquired Immunodeficiency SyndromeAdultBehavior, AddictiveHIV InfectionsHumansMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPrisonersPrisonsUkraineYoung AdultAttitudesHealthcare providersHIV/AIDSMethadoneOpioid substitution therapyUkraine

Identifiers

PMID25620732
PMCPMC4330127
OpenAlexW2013956670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.