Evidence map›Paper›PMID 25620439›Full record

ArticleClinical therapeutics2015

Effects of eliminating drug caps on racial differences in antidepressant use among dual enrollees with diabetes and depression.

Alyce S Adams, Stephen B Soumerai, Fang Zhang, Daniel Gilden, Marguerite Burns, Haiden A Huskamp, Connie Trinacty, Margarita Alegria, Robert F LeCates, Jennifer J Griggs and 2 more

Open access · greenAbstract read
In one paragraph

Article in Clinical therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Perceived appropriateness of medication adherence incentives.Journal of managed care & specialty pharmacy · 2021
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Effects of Transitioning to Medicare Part D on Access to Drugs for Medical Conditions among Dual Enrollees with Cancer.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Alyce S AdamsDivision of Research, Kaiser Permanente, Oakland, California. Electronic address: Alyce.S.Adams@kp.org.
Stephen B SoumeraiDepartment of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts.
Fang ZhangDepartment of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts.
Daniel GildenJEN Associates, Inc, Cambridge, Massachusetts.
Marguerite BurnsDepartment of Population Health Sciences, University of Wisconsin-Madison, Madison, Wisconsin.
Haiden A HuskampDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Connie TrinactyCenter for Health Research, Kaiser Permanente, Honolulu, Hawaii.
Margarita AlegriaCenter for Multicultural Mental Health Research, Cambridge Health Alliance and Harvard Medical School, Somerville, Massachusetts.
Robert F LeCatesDepartment of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts.
Jennifer J GriggsDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Dennis Ross-DegnanDepartment of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts.
Jeanne M MaddenDepartment of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, Massachusetts.
Harvard University · USAbt Global (United States) · USCambridge Health Alliance · USKaiser Permanente · USKaiser Permanente Center for Health Research · USUniversity of Michigan · USUniversity of Wisconsin–Madison · US

Funding

CRN4: Cancer Research Resources & Collaboration in Integrated Health Care SystemsU24CA171524 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2012 to 2016
$16.0M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Learnings in Diabetes Prevention from an Integrated Delivery SystemU58DP002721 · DP · KAISER FOUNDATION RESEARCH INSTITUTE · PI SCHMITTDIEL, JULIE A · 2010 to 2014
$2.5M
Drug Cost Containment Changes and Quality of Care for Mentally Ill Dual EnrolleesR01HS018577 · AHRQ · HARVARD PILGRIM HEALTH CARE, INC. · PI SOUMERAI, STEPHEN B · 2009 to 2012
$1.9M
Impact of Medicare Part D on Cancer and Diabetes Disparities among Dual EnrolleesR01AG032249 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI ADAMS, ALYCE SOPHIA · 2009 to 2011
$1.5M
Medication Adherence and Social Disparities in DiabetesR01DK080726 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2009 to 2012
$1.5M
Converting Public Health Insurance into Guideline-Concordant Mental Health CareK01MH092338 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI BURNS, MARGUERITE ELIZABETH · 2011 to 2015
$843k
Disparities in Diabetes Care: Health Plan Focus and Physician ResponsivenessK01HS018072 · AHRQ · KAISER FOUNDATION RESEARCH INSTITUTE · PI TRINACTY, CONNIE MAH · 2009 to 2013
$767k
AHRQ HHS 1R01 HS018577AHRQ HHS K01 HS018072AHRQ HHS K01HS018072AHRQ HHS R01 HS018577NCCDPHP CDC HHS U58 DP002721NCCDPHP CDC HHS U58DP002721NCI NIH HHS U24 CA171524NCI NIH HHS U24CA171524NIA NIH HHS 5R01AG032249NIA NIH HHS R01 AG032249NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30DK092924NIDDK NIH HHS R01 DK080726NIDDK NIH HHS R01DK080726NIMH NIH HHS K01 MH092338NIMH NIH HHS K01MH092338
6 · The paper itself

Abstract

purposeBlack patients with diabetes are at greater risk of underuse of antidepressants even when they have equal access to health insurance. This study aimed to evaluate the impact of removing a significant financial barrier to prescription medications (drug caps) on existing black-white disparities in antidepressant treatment rates among patients with diabetes and comorbid depression.

methodsWe used an interrupted time series with comparison series design and a 5% representative sample of all fee-for-service Medicare and Medicaid dual enrollees to evaluate the removal of drug caps on monthly antidepressant treatment rates. We evaluated the impact of drug cap removal on racial gaps in treatment by modeling the month-to-month white-black difference in use within age strata (younger than 65 years of age or 65 years of age or older). We compared adult dual enrollees with diabetes and comorbid depression living in states with strict drug caps (n = 221) and those without drug caps (n = 1133) before the policy change. Our primary outcome measures were the proportion of patients with any antidepressant use per month and the mean standardized monthly doses (SMDs) of antidepressants per month.

findingsThe removal of drug caps in strict drug cap states was associated with a sudden increase in the proportion of patients treated for depression (4 percentage points; 95% CI, 0.03-0.05, P < 0.0001) and in the intensity of antidepressant use (SMD: 0.05; 95% CI, 0.03-0.07, P < 0.001). Although antidepressant treatment rates increased for both white and black patients, the white-black treatment gap increased immediately after Part D (0.04 percentage points; 95% CI, 0.01-0.08) and grew over time (0.04 percentage points per month; 95% CI, 0.002-0.01; P < 0.001). IMPLICATIONS: Policies that remove financial barriers to medications may increase depression treatment rates among patients with diabetes overall while exacerbating treatment disparities. Tailored outreach may be needed to address nonfinancial barriers to mental health services use among black patients with diabetes.

Indexed as

AgedAntidepressive AgentsBlack or African AmericanDepressionDiabetes MellitusFee-for-Service PlansFemaleHumansInsurance, HealthMaleMedicaidMedicareMiddle AgedUnited StatesWhite PeopleAntidepressive Agentsaccess to carecomorbiditydiabetesdisparitieshealth policy

Identifiers

PMID25620439
PMCPMC4390474
OpenAlexW1967505352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.