ArticleAmerican journal of human genetics2015
Estimates of continental ancestry vary widely among individuals with the same mtDNA haplogroup.
Article in American journal of human genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Mitochondrial genetics through the lens of single-cell multi-omics.Nature genetics · 2024Review
- Feasibility and impact of haplogroup matching for mitochondrial replacement treatment.EMBO reports · 2023Article
- Forensic biogeographical ancestry inference: recent insights and current trends.Genes & genomics · 2023Review
- Uniparental markers reveal new insights on subcontinental ancestry and sex-biased admixture in Brazil.Molecular genetics and genomics : MGG · 2022Article
- Neither Donor nor Recipient Mitochondrial Haplotypes Are Associated with Unrelated Donor Transplant Outcomes: A Validation Study from the CIBMTR.Transplantation and cellular therapy · 2021Article
- Population inference based on mitochondrial DNA control region data by the nearest neighbors algorithm.International journal of legal medicine · 2021Article
- Worldwide human mitochondrial haplogroup distribution from urban sewage.Scientific reports · 2019Article
- Article
- Signs of continental ancestry in urban populations of Peru through autosomal STR loci and mitochondrial DNA typing.PloS one · 2018Article
- Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes.PloS one · 2018Article
- Association between mitochondrial DNA haplogroup and myelodysplastic syndromes.Genes, chromosomes & cancer · 2016Article
- Mitonuclear linkage disequilibrium in human populations.Proceedings. Biological sciences · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The association between a geographical region and an mtDNA haplogroup(s) has provided the basis for using mtDNA haplogroups to infer an individual's place of origin and genetic ancestry. Although it is well known that ancestry inferences using mtDNA haplogroups and those using genome-wide markers are frequently discrepant, little empirical information exists on the magnitude and scope of such discrepancies between multiple mtDNA haplogroups and worldwide populations. We compared genetic-ancestry inferences made by mtDNA-haplogroup membership to those made by autosomal SNPs in ∼940 samples of the Human Genome Diversity Panel and recently admixed populations from the 1000 Genomes Project. Continental-ancestry proportions often varied widely among individuals sharing the same mtDNA haplogroup. For only half of mtDNA haplogroups did the highest average continental-ancestry proportion match the highest continental-ancestry proportion of a majority of individuals with that haplogroup. Prediction of an individual's mtDNA haplogroup from his or her continental-ancestry proportions was often incorrect. Collectively, these results indicate that for most individuals in the worldwide populations sampled, mtDNA-haplogroup membership provides limited information about either continental ancestry or continental region of origin.
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