ArticleJournal of veterinary internal medicine2015
Serum cardiac troponin I concentrations in dogs with systemic inflammatory response syndrome.
Article in Journal of veterinary internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Chagas disease in a naturally-infected dog from Northeast Brazil: a case report.BMC veterinary research · 2025Article
- Effect of early stepwise cardiopulmonary rehabilitation on function and quality of life in sepsis patients.World journal of clinical cases · 2024Article
- Cardiac Troponin I and Electrocardiographic Evaluation in Hospitalized Cats with Systemic Inflammatory Response Syndrome.Veterinary sciences · 2023Article
- Evaluation of cardiac troponin I as a predictor of death in critically ill cats.Journal of veterinary internal medicine · 2023Article
- Autochthonous Babesia canis infections in 49 dogs in Germany.Journal of veterinary internal medicine · 2023Article
- Article
- Apolipoprotein A1 and serum amyloid A in dogs with sepsis and septic shock.Frontiers in veterinary science · 2023Article
- Electrocardiographic Findings and Cardiac Troponin I Assay in Dogs with SIRS Diagnosis.Veterinary sciences · 2022Article
- The Future of Biomarkers in Veterinary Medicine: Emerging Approaches and Associated Challenges.Animals : an open access journal from MDPI · 2022Review
- Biochemical, electrolytic, and cardiovascular evaluations in cats with urethral obstruction.Veterinary world · 2021Article
- Ambulatory electrocardiography and serum cardiac troponin I measurement in 21 dogs envenomated by the European adder (Vipera berus).Journal of veterinary internal medicine · 2020Article
- Evaluation of cardiac troponin I in serum and myocardium of rabbits with experimentally induced polymicrobial sepsis.Experimental animals · 2020Article
- The Causes of Canine Myocarditis and Myocardial Fibrosis Are Elusive by Targeted Molecular Testing: Retrospective Analysis and Literature Review.Veterinary pathology · 2019Review
- Evaluation of a high-sensitivity cardiac troponin I assay compared to a first-generation cardiac troponin I assay in Doberman Pinschers with and without dilated cardiomyopathy.Journal of veterinary internal medicine · 2019Article
- Diagnostic utility of cardiac troponin I in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2018Article
- Plasma procalcitonin concentrations predict organ dysfunction and outcome in dogs with sepsis.BMC veterinary research · 2018Article
- Cardiac Troponin I and Amino-Terminal Pro B-Type Natriuretic Peptide in Dogs With Stable Chronic Kidney Disease.Journal of veterinary internal medicine · 2017Observational
- Evaluation of cardiac troponin I in dogs presenting to the emergency room using a point-of-care assay.The Canadian veterinary journal = La revue veterinaire canadienne · 2016Observational
- Long-term management of high-grade atrioventricular block using cilostazol in a cat.JFMS open reportsArticle
- Cardiac Troponins in Dogs and Cats.Journal of veterinary internal medicineReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial injury can be detected by cardiac troponin I (cTnI) concentration, which appears to be a predictor of short-term death in critically ill patients. It is unknown if the best prognostic indicator of short-term survival is cTnI measurement at admission or at later time points. HYPOTHESIS/
objectivesMeasuring cTnI with a high-sensitivity (HS) test at different time points after admission may be a better short-term prognostic indicator than a single cTnI measurement at admission in dogs with systemic inflammatory response syndrome (SIRS). ANIMALS: Prospective, observational clinical study of 60 dogs with SIRS.
methodsCardiac troponin I concentration was measured in 133 serum samples, collected at days 1, 2, 3, and 5. Additionally, the acute patient physiologic and laboratory evaluation (APPLE) fast score was evaluated at admission. Prognostic capabilities of cTnI measurement and APPLE fast score for 28-day mortality were assessed by receiver operating characteristic curve analysis.
resultsForty-one dogs with SIRS that survived 28 days had significantly lower serum cTnI concentrations at admission (median, 0.09 ng/mL; P = .004) and at the peak time point (median, 0.23 ng/mL; P = .01) compared to 19 nonsurvivors (median at admission, 0.63 ng/mL; median at peak, 1.22 ng/mL). Area under the curve to predict survival, using cTnI was similar at admission (0.732) and at peak (0.708), and was 0.754 for the APPLE fast score. CONCLUSIONS AND CLINICAL IMPORTANCE: Increased cTnI concentration in dogs with SIRS is associated with poor outcome. Daily follow-up measurement of cTnI concentration provides no additional prognostic information for short-term mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.