ArticleJournal of experimental botany2015
Methylation of microRNA genes regulates gene expression in bisexual flower development in andromonoecious poplar.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 56 citations in OpenAlex.
- The landscape of cotton DNA methylation and its epigenetic regulation in Verticillium wilt resistance.Plant cell reports · 2026Article
- Genome-wide DNA methylation dynamics at "heading" stage of panicle and flag leaf in contrasting rice cultivars under field drought conditions.Frontiers in plant science · 2025Article
- Methylation of microRNA genes and its effect on secondary xylem development of stem in poplar.The plant genome · 2024Article
- Article
- The role of DNA methylation in the maintenance of phenotypic variation induced by grafting chimerism inHorticulture research · 2023Article
- Transcriptome and methylome changes in two contrasting mungbean genotypes in response to drought stress.BMC genomics · 2022Article
- Concerto on Chromatin: Interplays of Different Epigenetic Mechanisms in Plant Development and Environmental Adaptation.Plants (Basel, Switzerland) · 2021Review
- The Sw5a gene confers resistance to ToLCNDV and triggers an HR response after direct AC4 effector recognition.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Transcriptomic and epigenomic remodeling occurs during vascular cambium periodicity in Populus tomentosa.Horticulture research · 2021Article
- Differential DNA methylation and gene expression during development of reproductive and vegetative organs in Ilex species.Journal of plant research · 2021Article
- MicroRNAs in Woody Plants.Frontiers in plant science · 2021Review
- Title: Hypermethylation of miRNA Genes During Nodule Development.Frontiers in molecular biosciences · 2021Article
- Evidences for a role of two Y-specific genes in sex determination in Populus deltoides.Nature communications · 2020Article
- DNA methylation and its effects on gene expression during primary to secondary growth in poplar stems.BMC genomics · 2020Article
- Analysis of Alternative Splicing and Alternative Polyadenylation inFrontiers in genetics · 2020Article
- Integrated Methylome and Transcriptome Analysis between the CMS-D2 Line ZBA and Its Maintainer Line ZB in Upland Cotton.International journal of molecular sciences · 2019Article
- The poplar pangenome provides insights into the evolutionary history of the genus.Communications biology · 2019Article
- Sex and the flower - developmental aspects of sex chromosome evolution.Annals of botany · 2018Review
- Integrative Analysis of Transcriptomic and Methylomic Data in Photoperiod-Dependent Regulation of Cucumber Sex Expression.G3 (Bethesda, Md.) · 2018Article
- Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies showed sex-specific DNA methylation and expression of candidate genes in bisexual flowers of andromonoecious poplar, but the regulatory relationship between methylation and microRNAs (miRNAs) remains unclear. To investigate whether the methylation of miRNA genes regulates gene expression in bisexual flower development, the methylome, microRNA, and transcriptome were examined in female and male flowers of andromonoecious poplar. 27 636 methylated coding genes and 113 methylated miRNA genes were identified. In the coding genes, 64.5% of the methylated reads mapped to the gene body region; by contrast, 60.7% of methylated reads in miRNA genes mainly mapped in the 5' and 3' flanking regions. CHH methylation showed the highest methylation levels and CHG showed the lowest methylation levels. Correlation analysis showed a significant, negative, strand-specific correlation of methylation and miRNA gene expression (r=0.79, P <0.05). The methylated miRNA genes included eight long miRNAs (lmiRNAs) of 24 nucleotides and 11 miRNAs related to flower development. miRNA172b might play an important role in the regulation of bisexual flower development-related gene expression in andromonoecious poplar, via modification of methylation. Gynomonoecious, female, and male poplars were used to validate the methylation patterns of the miRNA172b gene, implying that hyper-methylation in andromonoecious and gynomonoecious poplar might function as an important regulator in bisexual flower development. Our data provide a useful resource for the study of flower development in poplar and improve our understanding of the effect of epigenetic regulation on genes other than protein-coding genes.
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