ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2015
Free-breathing T2* mapping using respiratory motion corrected averaging.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- The importance of spatial resolution in detecting chronic myocardial iron remnants following hemorrhagic myocardial infarction with T2* MRI.Biomedical physics & engineering express · 2026Article
- Groupwise image registration with edge-based loss for low-SNR cardiac MRI.Magnetic resonance in medicine · 2025Article
- Cardiac Phase-Resolved TBiomedicines · 2025Article
- Free-breathing MRI techniques for fat and RMagma (New York, N.Y.) · 2024Review
- Non-electrocardiogram-gated, free-breathing, off-resonance reduced, high-resolution, whole-heart myocardial TMagnetic resonance in medicine · 2024Article
- T2* quantification using multi-echo gradient echo sequences: a comparative study of different readout gradients.Scientific reports · 2023Article
- Article
- Evaluation of Hepatic Iron Overload Using a Contemporary 0.55 T MRI System.Journal of magnetic resonance imaging : JMRI · 2022Article
- The Road Toward Reproducibility of Parametric Mapping of the Heart: A Technical Review.Frontiers in cardiovascular medicine · 2022Review
- Free-breathing simultaneousMagnetic resonance in medicine · 2021Article
- Rosette Trajectories Enable Ungated, Motion-Robust, Simultaneous Cardiac and Liver TJournal of magnetic resonance imaging : JMRI · 2020Article
- Cardiac TJournal of magnetic resonance imaging : JMRI · 2020Review
- Free-breathing T2* mapping for MR myocardial iron assessment at 3 T.European radiology experimental · 2020Article
- Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel.Journal of the American College of Cardiology · 2019Review
- Patient specific prospective respiratory motion correction for efficient, free-breathing cardiovascular MRI.Magnetic resonance in medicine · 2019Article
- Cardiovascular Magnetic Resonance in Acute ST-Segment-Elevation Myocardial Infarction: Recent Advances, Controversies, and Future Directions.Circulation · 2018Review
- Role of T1 mapping as a complementary tool to T2* for non-invasive cardiac iron overload assessment.PloS one · 2018Article
- Review of Journal of Cardiovascular Magnetic Resonance (JCMR) 2015-2016 and transition of the JCMR office to Boston.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017Review
- Diagnostic performance of TJournal of magnetic resonance imaging : JMRI · 2017Article
- Semi-automated myocardial segmentation of bright blood multi-gradient echo images improves reproducibility of myocardial contours and T2* determination.Magma (New York, N.Y.) · 2017Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
backgroundPixel-wise T2* maps based on breath-held segmented image acquisition are prone to ghost artifacts in instances of poor breath-holding or cardiac arrhythmia. Single shot imaging is inherently immune to ghost type artifacts. We propose a free-breathing method based on respiratory motion corrected single shot imaging with averaging to improve the signal to noise ratio.
methodsImages were acquired using a multi-echo gradient recalled echo sequence and T2* maps were calculated at each pixel by exponential fitting. For 40 subjects (2 cohorts), two acquisition protocols were compared: (1) a breath-held, segmented acquisition, and (2) a free-breathing, single-shot multiple repetition respiratory motion corrected average. T2* measurements in the interventricular septum and liver were compared for the 2-methods in all studies with diagnostic image quality.
resultsIn cohort 1 (N = 28) with age 51.4 ± 17.6 (m ± SD) including 1 subject with severe myocardial iron overload, there were 8 non-diagnostic breath-held studies due to poor image quality resulting from ghost artifacts caused by respiratory motion or arrhythmias. In cohort 2 (N = 12) with age 30.9 ± 7.5 (m ± SD), including 7 subjects with severe myocardial iron overload and 4 subjects with mild iron overload, a single subject was unable to breath-hold. Free-breathing motion corrected T2* maps were of diagnostic quality in all 40 subjects. T2* measurements were in excellent agreement (In cohort #1, T2*FB = 0.95 x T2*BH + 0.41, r2 = 0.93, N = 39 measurements, and in cohort #2, T2*FB = 0.98 x T2*BH + 0.05, r2 > 0.99, N = 22 measurements).
conclusionsA free-breathing approach to T2* mapping is demonstrated to produce consistently good quality maps in the presence of respiratory motion and arrhythmias.
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