ArticlePloS one2015
Emotional disorders in pairs of patients and their family members during and after ICU stay.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PROSPECTIVE EVALUATION OF FAMILY CARE RITUALS IN THE ICU AND VALIDATION OF THE END-of-Life ScorING-System (ENDING-S), a Multicenter, Multinational Trial
The Health Promoting Conversations Intervention for Families With a Critically Ill Relative: A Pilot RCT
Development and Evaluation of a Nursing Intervention in the Patient Being Discharged From the Intensive Care Unit: a Protocol for Mixed Methods Research
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review.Anaesthesiology intensive therapy · 2023Pooled it
- Trial
- Feasibility and Efficacy of a Resiliency Intervention for the Prevention of Chronic Emotional Distress Among Survivor-Caregiver Dyads Admitted to the Neuroscience Intensive Care Unit: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Risk Factors for Post-Traumatic Stress Disorder Symptoms in Surrogate Decision-Makers of Patients with Chronic Critical Illness.Annals of the American Thoracic Society · 2018Trial
- Support Needs of Family Caregivers During Tracheostomy Transitions: A Mixed-Methods Study.Nursing open · 2026Article
- Anxiety, Depression, and Post-traumatic Stress Symptoms in Relatives of Patients Admitted to Intensive and Cardiac Intensive Care Units.Journal of clinical psychology in medical settings · 2026Article
- The Validity and Reliability of a Japanese Version of the Family Satisfaction in the Intensive Care Unit Survey: Multicenter Study.JMA journal · 2026Article
- Critical illness and recovery-learning from the shared experience of survivors and their families: A qualitative study.Journal of the Intensive Care Society · 2026Article
- Mental Health Needs of Families of Patients in Intensive Care Units and the Role of Mobile Health: Survey Study.JMIR formative research · 2026Article
- The Hidden Costs of ICU Caregiving: Economic, Mental Health and Spiritual Consequences.Healthcare (Basel, Switzerland) · 2026Article
- A Multicomponent Communication Intervention to Reduce the Psycho-Emotional Effects of Critical Illness in ICU Patients Related to Their Level of Consciousness: CONECTEM.Journal of clinical medicine · 2026Article
- Investigating the Feasibility, Usability, and Efficacy of a Mobile App to Reduce Anxiety and Depression in Families of Critical Care Cancer Patients: A Quasi-Experimental Pilot Study.Healthcare (Basel, Switzerland) · 2026Article
- Evaluating a stress management intervention effects on post-ICU syndrome in families: study protocol for a single-center, prospective, parallel-design, randomized controlled trial.Frontiers in psychology · 2026Article
- Anxiety, depression and distress in family members of people who have experienced a critical care admission: a systematic review and Bayesian meta-analysis.Journal of intensive care · 2025Article
- Disruptions in Sleep Health and Independent Associations with Psychological Distress in Close Family Members of Cardiac Arrest Survivors: A Prospective Study.Journal of cardiac failure · 2025Article
- A cross-sectional study to assess the perceived and unmet needs of the relatives/family members of patients admitted in intensive care unit.Indian journal of psychiatry · 2025Article
- Patient and Family Experience: Targets for Improvements in Care and Communication in the ICU.Journal of patient experience · 2025Article
- Care of the Patient Nearing the End of Life in the Neurointensive Care Unit.Neurocritical care · 2024Review
- Associations between Post-Intensive Care Syndrome Domains in Cardiac Arrest Survivors and Their Families One Month Post-Event.Journal of clinical medicine · 2024Article
- Family engagement in the care of infectious patients in intensive care units: A hybrid concept analysis.Nursing open · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPatients and family members undergo different experiences of suffering from emotional disorders during ICU stay and after ICU discharge. The purpose of this study was to compare the incidence of anxiety, depression and post-traumatic stress disorder (PTSD) symptoms in pairs (patient and respective family member), during stay at an open visit ICU and at 30 and 90-days post-ICU discharge. We hypothesized that there was a positive correlation with the severity of symptoms among pairs and different patterns of suffering over time.
methodsA prospective study was conducted in a 22-bed adult general ICU including patients with >48 hours stay. The Hospital Anxiety and Depression Scale (HADS) was completed by the pairs (patients/respective family member). Interviews were made by phone at 30 and 90-days post-ICU discharge using the Impact of Event Scale (IES) and the HADS. Multivariate models were constructed to predict IES score at 30 days for patients and family members.
resultsFour hundred and seventy one family members and 289 patients were interviewed in the ICU forming 184 pairs for analysis. Regarding HADS score, patients presented less symptoms than family members of patients who survived and who deceased at 30 and 90-days (p<0.001). However, family members of patients who deceased scored higher anxiety and depression symptoms (p = 0.048) at 90-days when compared with family members of patients who survived. Patients and family members at 30-days had a similar IES score, but it was higher in family members at 90-days (p = 0.019). For both family members and patients, age and symptoms of anxiety and depression during ICU were the major determinants for PTSD at 30-days.
conclusionsAnxiety, depression and PTSD symptoms were higher in family members than in the patients. Furthermore, these symptoms in family members persisted at 3 months, while they decreased in patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.