ArticleChemistry & biology2015
Antibacterial drug discovery: doing it right.
Article in Chemistry & biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Brief Overview of Approaches and Challenges in New Antibiotic Development: A Focus On Drug Repurposing.Frontiers in cellular and infection microbiology · 2021Review
- Review
- Allocyclinones, hyperchlorinated angucyclinones from Actinoallomurus.The Journal of antibiotics · 2017Article
- Synthesis and evaluation of functionalized benzoboroxoles as potentialTetrahedron · 2016Article
- Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.Scientific reports · 2015Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibacterial drug discovery needs to develop new strategies to identify attractive hit-target couples for more effective lead finding and optimization. In this issue of Chemistry & Biology, Park and coworkers describe a novel target-based whole cell combination screening approach resulting in the identification of new inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
Indexed as
Identifiers
25615950What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.