ArticleActa crystallographica. Section D, Biological crystallography2015
A national facility for biological cryo-electron microscopy.
Article in Acta crystallographica. Section D, Biological crystallography, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- Structure first - exploration and discovery with cryo-electron microscopy.Journal of cell science · 2026Review
- Advances in macromolecular crystallography at the Photon Factory: automation from crystallization to structural determination.Journal of synchrotron radiation · 2025Article
- Broadening access to cryoEM through centralized facilities.Trends in biochemical sciences · 2022Review
- Real-time cryo-electron microscopy data preprocessing with Warp.Nature methods · 2019Article
- Synchrotron science in the UK: NINA, the SRS and Diamond.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2019Article
- Review
- Using Scipion for stream image processing at Cryo-EM facilities.Journal of structural biology · 2018Article
- Where is crystallography going?Acta crystallographica. Section D, Structural biology · 2018Review
- Best practices for managing large CryoEM facilities.Journal of structural biology · 2017Article
- Trends in the Electron Microscopy Data Bank (EMDB).Acta crystallographica. Section D, Structural biology · 2017Article
- Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.Acta crystallographica. Section D, Structural biology · 2017Article
- Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2.eLife · 2016Article
- Review
- An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology.Methods (San Diego, Calif.) · 2016Article
- Cryo electron microscopy to determine the structure of macromolecular complexes.Methods (San Diego, Calif.) · 2016Review
- Databases and Archiving for CryoEM.Methods in enzymology · 2016Review
- Collaborative computational project for electron cryo-microscopy.Acta crystallographica. Section D, Biological crystallography · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Three-dimensional electron microscopy is an enormously powerful tool for structural biologists. It is now able to provide an understanding of the molecular machinery of cells, disease processes and the actions of pathogenic organisms from atomic detail through to the cellular context. However, cutting-edge research in this field requires very substantial resources for equipment, infrastructure and expertise. Here, a brief overview is provided of the plans for a UK national three-dimensional electron-microscopy facility for integrated structural biology to enable internationally leading research on the machinery of life. State-of-the-art equipment operated with expert support will be provided, optimized for both atomic-level single-particle analysis of purified macromolecules and complexes and for tomography of cell sections. The access to and organization of the facility will be modelled on the highly successful macromolecular crystallography (MX) synchrotron beamlines, and will be embedded at the Diamond Light Source, facilitating the development of user-friendly workflows providing near-real-time experimental feedback.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.