Evidence map›Paper›PMID 25615822›Full record

ArticleOrganic letters2015

Isolation of notoamide S and enantiomeric 6-epi-stephacidin A from the fungus Aspergillus amoenus: biogenetic implications.

Hikaru Kato, Takashi Nakahara, Kayo Sugimoto, Kanae Matsuo, Ippei Kagiyama, Jens C Frisvad, David H Sherman, Robert M Williams, Sachiko Tsukamoto

Erratum issuedAbstract read
In one paragraph

Article in Organic letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Taxonomy ofStudies in mycology · 2022
    Article
  4. Article
  5. Review
  6. Enantioselective assembly of multi-layerNational science review · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Marine Indole Alkaloids.Marine drugs · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hikaru KatoGraduate School of Pharmaceutical Sciences, Kumamoto University , 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.
Takashi Nakahara
Kayo Sugimoto
Kanae Matsuo
Ippei Kagiyama
Jens C Frisvad
David H Sherman
Robert M Williams
Sachiko Tsukamoto

Funding

TOTAL SYNTHESIS AND BIOSYNTHESIS OF BIOACTIVE SUBSTANCESR01CA070375 · NCI · COLORADO STATE UNIVERSITY-FORT COLLINS · PI SHERMAN, DAVID H, WILLIAMS, ROBERT MICHAEL · 1997 to 2018
$4.4M
NCI NIH HHS R01 CA070375
6 · The paper itself

Abstract

Notoamide S has been hypothesized to be a key biosynthetic intermediate for characteristic metabolites stephacidin A, notoamide B, and versicolamide B in Aspergillus sp. but has not yet been isolated. The isolation of notoamide S and an enantiomeric mixture of 6-epi-stephacidin A enriched with the (-)-isomer from Aspergillus amoenus is reported. The presence of (+)-versicolamide B suggests that the fungus possesses only the oxidase, which converts (+)-6-epi-stephacidin A into (+)-Versicolamide B, but not for (-)-6-epi-Stephacidin A.

Indexed as

AspergillusIndole AlkaloidsMolecular StructureNuclear Magnetic Resonance, BiomolecularStereoisomerismIndole Alkaloidsnotoamide Bnotoamide Sstephacidin Aversicolamide B

Identifiers

PMID25615822
PMCPMC4456087

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.