Evidence map›Paper›PMID 25615574›Full record

SynthesisPloS one2015

Genital chlamydia prevalence in Europe and non-European high income countries: systematic review and meta-analysis.

Shelagh M Redmond, Karin Alexander-Kisslig, Sarah C Woodhall, Ingrid V F van den Broek, Jan van Bergen, Helen Ward, Anneli Uusküla, Björn Herrmann, Berit Andersen, Hannelore M Götz and 2 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Who Is Best to Test? A Systematic Review of Chlamydia Infections in Switzerland.International journal of environmental research and public health · 2020
    Pooled it
  3. Pooled it
  4. Sexually transmitted infections · 2019
    Pooled it
  5. Prevalence ofSexually transmitted infections · 2018
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Chlamydia trachomatis prevalence in females in São Paulo, Brazil: 11 years' surveillance of the infection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. A systematic review of the prevalence of selected sexually transmitted infections in young people in Latin America.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Article
  19. Article
  20. Prevalence ofOpen forum infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shelagh M RedmondInstitute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, CH-3012, Bern, Switzerland.
Karin Alexander-KissligInstitute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, CH-3012, Bern, Switzerland.
Sarah C WoodhallHIV & STI Department, National Centre for Infectious Disease Surveillance and Control, Public Health England, 61 Colindale Avenue, London, NW9 5EQ, United Kingdom.
Ingrid V F van den BroekUnit of Epidemiology and Surveillance, RIVM/Centre for Infectious Disease Control Netherlands, PO Box 1, 3720 BA, Bilthoven, Netherlands.
Jan van BergenUniversity of Amsterdam, 1012 WX Amsterdam, Netherlands and STI AIDS Netherlands, Keizersgracht 390, 1016 GB, Amsterdam, Netherlands.
Helen WardInfectious Diseases Epidemiology, School of Public Health, Imperial College London, St Mary's Campus, Norfolk Place, London, W2 1PG, United Kingdom.
Anneli UuskülaDepartment of Public Health, University of Tartu, Ravila 19, 50411, Tartu, Estonia.
Björn HerrmannDepartment of Clinical Microbiology, Uppsala University Hospital, SE-751 85, Uppsala, Sweden.
Berit AndersenDepartment of Public Health Interventions, Randers Hospital, Skovlyvej, 8900, Randers, Denmark.
Hannelore M GötzDepartment of Infectious Disease Control, Municipal Public Health Service Rotterdam-Rijnmond, PO Box 70032, 3000 LP, Rotterdam, Netherlands.
Otilia SfetcuEuropean Centre for Disease Prevention and Control (ECDC), Tomtebodavägen 11 A, 17183, Stockholm, Sweden.
Nicola LowInstitute of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, CH-3012, Bern, Switzerland.

Funding

Medical Research Council G0601699Medical Research Council G0902120
6 · The paper itself

Abstract

backgroundAccurate information about the prevalence of Chlamydia trachomatis is needed to assess national prevention and control measures.

methodsWe systematically reviewed population-based cross-sectional studies that estimated chlamydia prevalence in European Union/European Economic Area (EU/EEA) Member States and non-European high income countries from January 1990 to August 2012. We examined results in forest plots, explored heterogeneity using the I² statistic, and conducted random effects meta-analysis if appropriate. Meta-regression was used to examine the relationship between study characteristics and chlamydia prevalence estimates.

resultsWe included 25 population-based studies from 11 EU/EEA countries and 14 studies from five other high income countries. Four EU/EEA Member States reported on nationally representative surveys of sexually experienced adults aged 18-26 years (response rates 52-71%). In women, chlamydia point prevalence estimates ranged from 3.0-5.3%; the pooled average of these estimates was 3.6% (95% CI 2.4, 4.8, I² 0%). In men, estimates ranged from 2.4-7.3% (pooled average 3.5%; 95% CI 1.9, 5.2, I² 27%). Estimates in EU/EEA Member States were statistically consistent with those in other high income countries (I² 0% for women, 6% for men). There was statistical evidence of an association between survey response rate and estimated chlamydia prevalence; estimates were higher in surveys with lower response rates, (p = 0.003 in women, 0.018 in men).

conclusionsPopulation-based surveys that estimate chlamydia prevalence are at risk of participation bias owing to low response rates. Estimates obtained in nationally representative samples of the general population of EU/EEA Member States are similar to estimates from other high income countries.

Indexed as

AdolescentAdultChlamydia InfectionsCross-Sectional StudiesDeveloped CountriesEuropeFemaleGenitaliaHumansMalePrevalenceRandom AllocationYoung Adult

Identifiers

PMID25615574
PMCPMC4304822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.