ArticleJournal of biomedical materials research. Part B, Applied biomaterials2016
Brushite foams--the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties.
Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 27 citations in OpenAlex.
- A clinically relevant formulation for direct administration of nerve specific fluorophores to mitigate iatrogenic nerve injury.Biomaterials · 2022Article
- Impact of small molecule and reverse poloxamer addition on the micellization and gelation mechanisms of poloxamer hydrogels.Colloids and surfaces. A, Physicochemical and engineering aspects · 2022Article
- Development of highly porous calcium phosphate bone cements applying nonionic surface active agents.RSC advances · 2021Article
- Risedronate-Loaded Macroporous Gel Foam Enriched with Nanohydroxyapatite: Preparation, Characterization, and Osteogenic Activity Evaluation Using Saos-2 Cells.AAPS PharmSciTech · 2019Article
- Peri-tumor administration of 5-fluorouracil sol-gel using a hollow microneedle for treatment of gastric cancer.Drug delivery · 2018Article
- Brushite foams--the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties.Journal of biomedical materials research. Part B, Applied biomaterials · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, using two different synthetic surfactants, Tween® 80 and Pluronic® F-127. The macropores formed in the Pluronic samples were both smaller and less homogeneously distributed compared with the pores formed in the Tween samples. The porosity and compressive strength (CS) were comparable to previously developed hydroxyapatite foams. The cement foam containing Tween, 0.5M citric acid in the liquid, 1 mass% of disodium dihydrogen pyrophosphate mixed in the powder and a liquid to powder ratio of 0.43 mL/g, showed the highest porosity values (76% total and 56% macroporosity), while the CS was >1 MPa, that is, the hardened cement could be handled without rupture of the foamed structure. The investigated brushite foams show potential for future clinical use, both as bone void fillers and as scaffolds for in vitro bone regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.