ArticleInternational cardiovascular research journal2014
Incidence and outcome of documented fungal endocarditis.
Article in International cardiovascular research journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Pooled it
- Antifungal Efficacy of Amphotericin B in Candida Albicans Endocarditis Therapy: Systematic Review.Brazilian journal of cardiovascular surgery · 2020Pooled it
- Review
- Cryptococcal Endocarditis in Humans-A Narrative Review.Pathogens (Basel, Switzerland) · 2025Review
- The Prevalence and Characteristics of Infective Endocarditis in Liver Transplant Recipients: Insights From National Inpatient Sample Database.Clinical cardiology · 2025Article
- Article
- UnderstandingCells · 2023Article
- Endocarditis caused by Aspergillus fumigatus in a patient 9 months after COVID-19 infection recovery: a case report and review of the literature.Journal of medical case reports · 2023Review
- Candida Infectious Endocarditis and Implantable Cardiac Device Infections.Mycopathologia · 2023Review
- Article
- Article
- Prosthetic valve endocarditis due toAccess microbiology · 2023Article
- Cryptococcus neoformans endocarditis in an immunocompetentpatient a case report.BMC cardiovascular disorders · 2022Article
- Article
- Antibacterial and Antifungal Management in Relation to the Clinical Characteristics of Elderly Patients with Infective Endocarditis: A Retrospective Analysis.Antibiotics (Basel, Switzerland) · 2022Article
- Comparison of the fungicidal efficacy of photodynamic therapy with methylene blue, silver nanoparticle, and their conjugation on oralCurrent medical mycology · 2020Article
- Article
- Successful treatment of Aspergillus mural endocarditis in malignant lymphoma using a combined antifungal and surgical approach: a case report.Surgical case reports · 2020Article
- Fungal endocarditis resembling primary cardiac malignancy in a patient with B-cell ALL with culture confirmation.Radiology case reports · 2020Article
- Fungal endocarditis of native valves.BMJ case reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFungal endocarditis, the most severe form of infective endocarditis, is characterized by excessive mortality and morbidity.
objectivesThe present study aimed to analyze the characteristics of fungal endocarditis to improve the management of these patients. MATERIALS AND
methodsIn this cross-sectional study, vegetations on the mitral or tricuspid valves and embolic material surgically removed from the patients with suspected infective endocarditis between December 2009 and November 2011 were examined for fungal infection by direct smear and culture, and the susceptibility patterns of the isolated species were determined. Then, blood samples were cultured on BACTEC media and real-time PCR was done with blood and tissue samples.
resultsOf the 31 patients with suspected infective endocarditis who did not respond to antibacterial therapy, 11 had confirmed fungal endocarditis. The most frequent predisposing risk factors were previous surgery and drug abuse. The organisms isolated were Aspergillus spp. and Candida albicans. Resistance to amphotericin B and itraconazole was observed in Aspergillus species, and to fluconazole in Candida albicans. Positive PCR results were obtained in blood and tissue samples.
conclusionsFungal endocarditis should be considered in the patients not responsive to antimicrobials. Moreover, management of these patients can be improved with molecular diagnostic methods and by determining the susceptibility patterns of the etiologic agents.
Indexed as
Identifiers
25614858PMC4302502W2116995930What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.