Evidence map›Paper›PMID 25614606›Full record

ArticleGenetics2015

Locally epistatic genomic relationship matrices for genomic association and prediction.

Deniz Akdemir, Jean-Luc Jannink

Abstract read
In one paragraph

Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Non-linear kernel methods for genomic prediction of soybean yield and quality in multi-environment trials.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  12. Genomic Prediction Methods Accounting for Nonadditive Genetic Effects.Methods in molecular biology (Clifton, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Deniz AkdemirDepartment of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853 da346@cornell.edu.ORCID http://orcid.org/0000-0003-0553-6798
Jean-Luc JanninkDepartment of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In plant and animal breeding studies a distinction is made between the genetic value (additive plus epistatic genetic effects) and the breeding value (additive genetic effects) of an individual since it is expected that some of the epistatic genetic effects will be lost due to recombination. In this article, we argue that the breeder can take advantage of the epistatic marker effects in regions of low recombination. The models introduced here aim to estimate local epistatic line heritability by using genetic map information and combining local additive and epistatic effects. To this end, we have used semiparametric mixed models with multiple local genomic relationship matrices with hierarchical designs. Elastic-net postprocessing was used to introduce sparsity. Our models produce good predictive performance along with useful explanatory information.

Indexed as

BreedingEpistasis, GeneticGenomeModels, GeneticAnimalsPlantsRecombination, Geneticepistasisgenomic selectionGenPredmixed modelsshared data resource

Identifiers

PMID25614606
PMCPMC4349077

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.