Evidence map›Paper›PMID 25614158›Full record

ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2015

Survival of rhinoviruses on human fingers.

A G L'Huillier, C Tapparel, L Turin, P Boquete-Suter, Y Thomas, L Kaiser

Open access · bronzeAbstract read
In one paragraph

Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Vaccines for the common cold.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
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  5. Observational
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  8. Out of the 'host' box: extreme off-host conditions alter the infectivity and virulence of a parasitic bacterium.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  9. Article
  10. Rapid syndromic testing for respiratory viral infections in children attending the emergency department during COVID-19 pandemic in Lille, France, 2021-2022.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

A G L'HuillierLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland. Electronic address: Arnaud.Lhuillier@hcuge.ch.
C TapparelLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland; Microbiology and Molecular Medicine, University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland.
L TurinLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland.
P Boquete-SuterLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland.
Y ThomasLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland.
L KaiserLaboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University of Geneva, Geneva, Switzerland.
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhinovirus is the main cause of the common cold, which remains the most frequent infection worldwide among humans. Knowledge and understanding of the rhinovirus transmission route is important to reduce morbidity as only preventive measures are effective. In this study, we investigated the potential of rhinovirus to survive on fingers. Rhinovirus-B14 was deposited on fingers for 30, 60, 90 and 120 min. Survival was defined as the ability of the virus to grow after 7 days, confirmed by immunofluorescence. Rhinovirus survival was not dependent on incubation time on fingers. Droplet disruption had no influence on survival. Survival was frequent with high rhinovirus concentrations, but rare with low-concentration droplets, which corresponded to the usual rhinovirus concentrations in mucus observed in children and adults, respectively. Our study confirms that rhinovirus infectiousness is related to the viral concentration in droplets and suggests that children represent the main transmission source, which occurs only rarely via adults. It confirms also that rhinovirus hand-related transmission is possible and supports hand hygiene as a key prevention measure.

Indexed as

Microbial ViabilityAdultChildChild, PreschoolFingersHealthy VolunteersHumansRhinovirusTime FactorsFingershand hygienepicornavirusrhinovirussurvivaltransmission

Identifiers

PMID25614158
PMCPMC7129024
OpenAlexW2056416587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.