Evidence map›Paper›PMID 25614127›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2015

Dementia severity and the longitudinal costs of informal care in the Cache County population.

Gail B Rattinger, Sarah Schwartz, C Daniel Mullins, Chris Corcoran, Ilene H Zuckerman, Chelsea Sanders, Maria C Norton, Elizabeth B Fauth, Jeannie-Marie S Leoutsakos, Constantine G Lyketsos and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  11. 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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  17. Hearing Loss, Psychiatric Symptoms, and Cognitive Decline: An Increasingly Important Triad in Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gail B RattingerPharmacy Practice Division, School of Pharmacy, Fairleigh Dickinson University, Florham Park, NJ, USA.
Sarah SchwartzCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA; Department of Mathematics and Statistics, Utah State University, Logan, UT, USA.
C Daniel MullinsPharmaceutical Health Services Research Department, University of Maryland Baltimore School of Pharmacy, Baltimore, MD, USA.
Chris CorcoranCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA; Department of Mathematics and Statistics, Utah State University, Logan, UT, USA.
Ilene H ZuckermanPharmaceutical Health Services Research Department, University of Maryland Baltimore School of Pharmacy, Baltimore, MD, USA.
Chelsea SandersDepartment of Psychology, Utah State University, Logan, UT, USA.
Maria C NortonCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA; Department of Family, Consumer and Human Development, Utah State University, Logan, UT, USA.
Elizabeth B FauthCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA; Department of Family, Consumer and Human Development, Utah State University, Logan, UT, USA.
Jeannie-Marie S LeoutsakosJohns Hopkins Bayview Medical Center, Baltimore, MD, USA.
Constantine G LyketsosJohns Hopkins Bayview Medical Center, Baltimore, MD, USA.
JoAnn T TschanzCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA; Department of Psychology, Utah State University, Logan, UT, USA. Electronic address: joann.tschanz@usu.edu.

Funding

'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S. · 1985 to 2019
$37.6M
EPIDEMIOLOGY OF DEMENTIA IN CACHE COUNTY, UTAHR01AG011380 · NIA · JOHNS HOPKINS UNIVERSITY · PI WELSH-BOHMER, KATHLEEN ANNE · 1994 to 2009
$12.2M
Progression of Dementia: A Population StudyR01AG021136 · NIA · UTAH STATE UNIVERSITY · PI LYKETSOS, CONSTANTINE G, TSCHANZ, JOANN T · 2002 to 2010
$6.0M
NIA NIH HHS P50 AG005146NIA NIH HHS R01 AG011380NIA NIH HHS R01 AG021136NIA NIH HHS R01AG11380NIA NIH HHS R01AG21136
6 · The paper itself

Abstract

backgroundDementia costs are critical for influencing healthcare policy, but limited longitudinal information exists. We examined longitudinal informal care costs of dementia in a population-based sample.

methodsData from the Cache County Study included dementia onset, duration, and severity assessed by the Mini-Mental State Examination (MMSE), Clinical Dementia Rating Scale (CDR), and Neuropsychiatric Inventory (NPI). Informal costs of daily care (COC) was estimated based on median Utah wages. Mixed models estimated the relationship between severity and longitudinal COC in separate models for MMSE and CDR.

resultsTwo hundred and eighty-seven subjects (53% female, mean (standard deviation) age was 82.3 (5.9) years) participated. Overall COC increased by 18% per year. COC was 6% lower per MMSE-point increase and compared with very mild dementia, COC increased over twofold for mild, fivefold for moderate, and sixfold for severe dementia on the CDR.

conclusionsGreater dementia severity predicted higher costs. Disease management strategies addressing dementia progression may curb costs.

Indexed as

AgedAged, 80 and overAge DistributionAge FactorsCaregiversCommunity Health PlanningDementiaFemaleHumansLongitudinal StudiesMaleOutcome Assessment, Health CarePatient CarePsychiatric Status Rating ScalesRetrospective StudiesTime FactorsAlzheimer's disease costsCostsDementia longitudinal costsLongitudinal caregiving costsLongitudinal informal dementia

Identifiers

PMID25614127
PMCPMC4506892

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.