ArticleScientific reports2015
Evolutionary analysis of rubella viruses in mainland China during 2010-2012: endemic circulation of genotype 1E and introductions of genotype 2B.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Design of a chimaeric antigen and its use in the detection of IgG antibodies against rubella virus.Virology journal · 2022Article
- Importation and circulation of rubella virus lineages 1E-L2 and 2B-L2c between 2018 and 2021 in China: Virus evolution and spatial-temporal transmission characteristics.Virus evolution · 2022Article
- Phylogeography of rubella virus in Asia: Vaccination and demography shape synchronous outbreaks.Epidemics · 2019Article
- Progress towards rubella elimination after implementation of rubella immunization for over 20 years in Shandong province, China.Scientific reports · 2017Article
- Evolutionary analysis of mumps viruses of genotype F collected in mainland China in 2001-2015.Scientific reports · 2017Article
- Genetic diversity of currently circulating rubella viruses: a need to define more precise viral groups.The Journal of general virology · 2017Article
- Molecular Epidemiology of Rubella Virus Strains Detected Around the Time of the 2012-2013 Epidemic in Japan.Frontiers in microbiology · 2017Article
- Analysis of complete genomes of the rubella virus genotypes 1E and 2B which circulated in China, 2000-2013.Scientific reports · 2016Article
- Vaccination in secondary school students expedites rubella control and prevents congenital rubella syndrome.BMC infectious diseases · 2016Article
- Epidemiological and molecular investigation of a rubella outbreak, Romania, 2011 to 2012.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016Article
- Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens.Genome medicine · 2016Article
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34 authors.
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Abstract
Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010-2012 were sequenced and analyzed, significantly extending previous reports on limited numbers of viruses collected before 2010. Only viruses of genotypes 1E and 2B were found. Genotype 1E viruses were found in all 24 provinces. Genotype 1E viruses were likely introduced into mainland China around 1997 and endemic transmission of primarily one lineage became established. Viruses reported here from 2010-2012 are largely in a single cluster within this lineage. Genotype 2B viruses were rarely detected in China prior to 2010. This report documents a previously undetected 2B lineage, which likely became endemic in eastern provinces of China between 2010 and 2012. Bayesian analyses were performed to estimate the evolutionary rates and dates of appearance of the genotype 1E and 2B viral linages in China. A skyline plot of viral population diversity did not provide evidence of reduction of diversity as a result of vaccination, but should be useful as a baseline for such reductions as vaccination programs for rubella become widespread in mainland China.
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