Evidence map›Paper›PMID 25612013›Full record

ArticleChest2015

Impact of OSA on cardiovascular events after coronary artery bypass surgery.

Carlos Henrique G Uchôa, Naury de Jesus Danzi-Soares, Flávia S Nunes, Altay A L de Souza, Flávia B Nerbass, Rodrigo P Pedrosa, Luiz Antonio M César, Geraldo Lorenzi-Filho, Luciano F Drager

Abstract read
PubMed Publisher
In one paragraph

Article in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 8 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 8 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Feasibility of Transcatheter Caval Valve Implantation to ImproveFrontiers in cardiovascular medicine · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carlos Henrique G UchôaSleep Laboratory, Pulmonary Division, University of São Paulo Medical School, São Paulo; Hypertension Unit, University of São Paulo Medical School, São Paulo.
Naury de Jesus Danzi-SoaresSleep Laboratory, Pulmonary Division, University of São Paulo Medical School, São Paulo.
Flávia S NunesSleep Laboratory, Pulmonary Division, University of São Paulo Medical School, São Paulo.
Altay A L de SouzaPhysicobiology Department, Federal University, São Paulo.
Flávia B NerbassSleep Laboratory, Pulmonary Division, University of São Paulo Medical School, São Paulo.
Rodrigo P PedrosaSleep and Heart Laboratory, Pronto Socorro Cardiológico de Pernambuco (PROCAPE) da Universidade de Pernambuco, Pernambuco, Brazil.
Luiz Antonio M CésarClinical Unit of Chronic Coronary Heart Disease, Heart Institute (InCor), University of São Paulo Medical School, São Paulo.
Geraldo Lorenzi-FilhoSleep Laboratory, Pulmonary Division, University of São Paulo Medical School, São Paulo.
Luciano F DragerHypertension Unit, University of São Paulo Medical School, São Paulo; Hypertension Unit, Renal Division, University of São Paulo Medical School, São Paulo. Electronic address: luciano.drager@incor.usp.br.
Universidade de São Paulo · BRUniversidade de Pernambuco · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of OSA on new cardiovascular events in patients undergoing coronary artery bypass graft (CABG) surgery is poorly explored.

methodsConsecutive patients referred for CABG underwent clinical evaluation and standard polysomnography in the preoperative period. CABG surgery data, including percentage of off-pump and on-pump CABG, number of grafts, and intraoperative complications, were collected. The primary end point was major adverse cardiac or cerebrovascular events (MACCEs) (combined events of all-cause death, myocardial infarction, repeated revascularization, and cerebrovascular events). Secondary end points included individual MACCEs, typical angina, and arrhythmias. Patients were evaluated at 30 days (short-term) and up to 6.1 years (long term) after CABG.

resultsWe studied 67 patients (50 men; mean age, 58 ± 8 years; mean BMI, 28.5 ± 4.1 kg/m2). OSA (apnea-hypopnea index ≥ 15 events/h) was present in 56% of the population. The patients were followed for a mean of 4.5 years (range, 3.2-6.1 years). No differences were observed in the short-term follow-up. In contrast, MACCE (35% vs 16%, P = .02), new revascularization (19% vs 0%, P = .01), episodes of typical angina (30% vs 7%, P = .02), and atrial fibrillation (22% vs 0%, P = .0068) were more common in patients with than without OSA in the long-term follow-up. OSA was an independent factor associated with the occurrence of MACCE, repeated revascularization, typical angina, and atrial fibrillation in the multivariate analysis.

conclusionsOSA is independently associated with a higher rate of long-term cardiovascular events after CABG and may have prognostic and economic significance in CABG surgery.

Indexed as

Coronary Artery BypassCardiovascular DiseasesCerebrovascular DisordersFemaleHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesSleep Apnea, ObstructiveTime Factors

Identifiers

PMID25612013
OpenAlexW1837484436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.