ArticleNeuroImage. Clinical2015
Increased cortical surface area and gyrification following long-term survival from early monocular enucleation.
Article in NeuroImage. Clinical, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Pulvinar and total thalamus volumes are preserved following early monocular enucleation.Frontiers in neuroscience · 2026Article
- Timing of eye removal influences low-vision quality of life and self-perception of facial appearance in people with one eye.PloS one · 2025Article
- Effects of early monocular enucleation on cortical spreading depression in well-nourished and malnourished adult rats.Experimental brain research · 2024Article
- Perception of the McGurk effect in people with one eye depends on whether the eye is removed during infancy or adulthood.Frontiers in neuroscience · 2023Article
- Abnormal cortical morphology in children and adolescents with intermittent exotropia.Frontiers in neuroscience · 2022Article
- Altered Spontaneous Brain Activity and Network Property in Patients With Congenital Monocular Blindness.Frontiers in neurology · 2022Article
- Brain Activation for Audiovisual Information in People With One Eye Compared to Binocular and Eye-Patched Viewing Controls.Frontiers in neuroscience · 2020Article
- More than meets the eye: Longitudinal visual system neurodevelopment in very preterm children and anophthalmia.NeuroImage. Clinical · 2020Article
- Effect of dexmedetomidine anesthesia on respiratory function in pediatric patients undergoing retinoblastoma resection.Oncology letters · 2019Article
- Altered white matter structure in auditory tracts following early monocular enucleation.NeuroImage. Clinical · 2019Article
- Altered white matter structure in the visual system following early monocular enucleation.Human brain mapping · 2018Article
- Retinoblastoma.Nature reviews. Disease primers · 2015Review
- Evidence of multisensory plasticity: Asymmetrical medial geniculate body in people with one eye.NeuroImage. Clinical · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeRetinoblastoma is typically diagnosed before 5 years of age and is often treated by enucleation (surgical removal) of the cancerous eye. Here, we sought to characterize morphological changes of the cortex following long-term survival from early monocular enucleation.
methodsNine adults with early right-eye enucleation (≤48 months of age) due to retinoblastoma were compared to 18 binocularly intact controls. Surface area, cortical thickness, and gyrification estimates were obtained from T1 weighted images and group differences were examined.
resultsEarly monocular enucleation was associated with increased surface area and/or gyrification in visual (i.e., V1, inferior temporal), auditory (i.e., supramarginal), and multisensory (i.e., superior temporal, inferior parietal, superior parietal) cortices compared with controls. Visual cortex increases were restricted to the right hemisphere contralateral to the remaining eye, consistent with previous subcortical data showing asymmetrical lateral geniculate nucleus volume following early monocular enucleation.
conclusionsAltered morphological development of visual, auditory, and multisensory regions occurs subsequent to long-time survival from early eye loss.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.