Evidence map›Paper›PMID 25610752›Full record

ArticleJournal of clinical trials2014

Rhodiola rosea therapy for major depressive disorder: a study protocol for a randomized, double-blind, placebo- controlled trial.

Jun J Mao, Qing S Li, Irene Soeller, Sharon X Xie, Jay D Amsterdam

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2015
    Trial
  2. Review
  3. Controlled Cultivation ConfersAntioxidants (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Comparison of Effect ofJournal of clinical and diagnostic research : JCDR · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun J MaoDepartment of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA ; Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA ; Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Qing S LiDepartment of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Irene SoellerDepartment of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Sharon X XieCenter for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Jay D AmsterdamDepression Research Unit, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
University of Pennsylvania · US

Funding

Elucidating the placebo effects of acupuncture: hot flashes as a clinical modelK23AT004112 · NCCIH · UNIVERSITY OF PENNSYLVANIA · PI MAO, JUN J · 2008 to 2012
$659k
Rhodiola rosea Therapy of Major Depressive DisorderR21AT005230 · NCCIH · UNIVERSITY OF PENNSYLVANIA · PI MAO, JUN J · 2010 to 2012
$636k
NCCIH NIH HHS K23 AT004112NCCIH NIH HHS R21 AT005230
6 · The paper itself

Abstract

backgroundRhodiola rosea ( METHODS /

designSubjects with MDD not receiving antidepressant therapy will be randomized to either DISCUSSION: This study will provide valuable preliminary information on the safety and efficacy data of

Indexed as

Alternative MedicineBotanical TherapyDepressionHerbal TherapyMajor Depressive DisorderRhodiola roseaR. rosea

Identifiers

PMID25610752
PMCPMC4297663
OpenAlexW2160340176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.