ArticleVeterinary research forum : an international quarterly journal2014
Protective effects of pomegranate seed oil on ovariectomized rats as a model of postmenopausal osteoporosis: A multi-detector computed tomography evaluation.
Article in Veterinary research forum : an international quarterly journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Beneficial Effects of Pomegranate Extracts for Benign Gynecologic Disorders.Reproductive sciences (Thousand Oaks, Calif.) · 2025Review
- Rheological, physico-sensory and antioxidant properties of punicic acid rich wheat bread.Journal of food science and technology · 2020Article
- Role of dietary bioactive natural products in estrogen receptor-positive breast cancer.Seminars in cancer biology · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pomegranate seed oil (PSO), containing 17-α-estradiol, is one of the newly found phytosterols with synergistic health effects on estrogen related physiological conditions. Herein, PSO was assessed for its potential improving effects on bone characteristics in a rat model of menopausal syndrome. Three month old non-pregnant female Wistar rats (n = 30) were either sham-operated (SHAM) or ovariectomized (OVX), each divided into two further groups receiving 0.1 mL PSO or the same volume of paraffin oil as placebo. Before the operation and 67 days after it, multi-detector computed tomography (MDCT) scanning was performed with the identical setup option for the scanner to measure the bone mineral density (BMD) in body of 12(th) thoracic vertebra, 1(st) to 6(th) lumbar vertebra and sacrum. This study revealed that bone density of 1(st), 3(rd), 5(th), 6(th) and sacrum body were significantly different between OVX and SHAM groups during the study period. In conclusion, PSO during 67 days study could not completely prevent the osteoporotic effects caused by ovariectomy in vertebral column of rats.
Indexed as
Identifiers
25610577PMC4299991W2150697089What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.