Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate.

Myeonggu Son, Gyudo Lee, Jongsang Son, Seungyeop Choi, Youngho Kim, Sei-Young Lee, Young-Ro Yoon, Dae Sung Yoon, Sang Woo Lee

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Article in Biomicrofluidics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

9 authors.

Myeonggu SonDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Gyudo LeeDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Jongsang SonDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Seungyeop ChoiDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Youngho KimDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Sei-Young LeeDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Young-Ro YoonDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Dae Sung YoonSchool of Biomedical Engineering, Korea University , Seoul 136-703, South Korea.

Sang Woo LeeDepartment of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The random walk of spherical living cells on a silicon dioxide glassy substrate was studied experimentally and numerically. This random walk trajectory exhibited erratic dancing, which seemingly obeyed anomalous diffusion (i.e., Lévy-like walk) rather than normal diffusion. Moreover, the angular distribution (-π to π) of the cells' trajectory followed a "U-shaped pattern" in comparison to the uniform distribution seen in the movements of negatively charged polystyrene microspheres. These effects could be attributable to the homeostasis-driven structural resilient character of cells and physical interactions derived from temporarily retained nonspecific binding due to weak forces between the cells and substrates. Our results provide new insights into the stochastic behavior of mesoscopic biological particles with respect to structural properties and physical interactions.

Identifiers

PMID25610514

DOI10.1063/1.4905577

PMCPMC4288934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.