Evidence map›Paper›PMID 25610512›Full record

ArticleBiomicrofluidics2014

Ripple structure-generated hybrid electrokinetics for on-chip mixing and separating of functionalized beads.

I-Fang Cheng, Sheng-Chuan Chiang, Cheng-Che Chung, Trai-Ming Yeh, Hsien-Chang Chang

Abstract read
In one paragraph

Article in Biomicrofluidics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I-Fang ChengNational Nano Device Laboratories, National Applied Research Laboratories , Tainan, Taiwan.
Sheng-Chuan ChiangDepartment of Biomedical Engineering, National Cheng Kung University , Tainan, Taiwan.ORCID 0000-0001-8645-3534
Cheng-Che ChungInstitute of Nanotechnology and Microsystems Engineering, National Cheng Kung University , Tainan, Taiwan.
Trai-Ming YehMedical Laboratory Science and Biotechnology, National Cheng Kung University , Tainan, Taiwan.
Hsien-Chang Chang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present an electrokinetics-based microfluidic platform that is capable of on-chip manipulating, mixing, and separating microparticles through adjusting the interrelated magnitudes of dielectrophoresis and AC electroosmosis. Hybrid electrokinetic phenomenon is generated from an electric field-induced micro-ripple structure made of ultraviolet-curable glue. Size-dependent particle separation and selective removal over the ripple structure is demonstrated successfully. Varying the waveform from sine-wave to square-wave allows generating a fluid convection at specific positions to mix the antibody-functionalized beads and antigen. Potential application in the bead-based immunoassay was also demonstrated for immuno-reaction and subsequently separating the bead-bead aggregate and non-binding beads on-chip.

Identifiers

PMID25610512
PMCPMC4291454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.