Evidence map›Paper›PMID 25610388›Full record

ReviewFrontiers in human neuroscience2014

Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness.

Carlo Cavaliere, Marco Aiello, Carol Di Perri, Davinia Fernandez-Espejo, Adrian M Owen, Andrea Soddu

Abstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlo CavaliereComa Science Group, Cyclotron Research Center and Neurology Department, University and University Hospital of Liege Liege, Belgium.
Marco AielloIRCCS SDN, Istituto Ricerca Diagnostica Nucleare Naples, Italy.
Carol Di PerriNeuroradiology Department, National Neurological Institute C. Mondino Pavia, Italy.
Davinia Fernandez-EspejoPsychology Department, Brain and Mind Institute, University of Western Ontario London ON, Canada.
Adrian M OwenPsychology Department, Brain and Mind Institute, University of Western Ontario London ON, Canada.
Andrea SodduPhysics and Astronomy Department, Brain and Mind Institute, University of Western Ontario London ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progress in neuroimaging has yielded new powerful tools which, potentially, can be applied to clinical populations, improve the diagnosis of neurological disorders and predict outcome. At present, the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements of behavior, with an emerging role for neuroimaging techniques. In this review we focus on white matter alterations measured using Diffusion Tensor Imaging on patients with consciousness disorders, examining the most common diffusion imaging acquisition protocols and considering the main issues related to diffusion imaging analyses. We conclude by considering some of the remaining challenges to overcome, the existing knowledge gaps and the potential role of neuroimaging in understanding the pathogenesis and clinical features of disorders of consciousness.

Indexed as

braincomaconsciousnessdiffusion tensor imagingtractography

Identifiers

PMID25610388
PMCPMC4285098

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.