Evidence map›Paper›PMID 25609993›Full record

ReviewThe application of clinical genetics2015

The genetics of Ménière's disease.

Giuseppe Chiarella, C Petrolo, E Cassandro

Abstract readReview
In one paragraph

Review in The application of clinical genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Intratympanic gentamicin for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Intratympanic corticosteroids for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Surgical interventions for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  4. Systemic pharmacological interventions for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  5. ZDHHC5 may regulate the function of NKT cells and the immune response in Meniere's disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  6. Review
  7. The Impact of Genetic Factors in Ménière's Disease.International journal of molecular sciences · 2026
    Review
  8. Article
  9. Immunological mechanisms in Meniere's disease.Frontiers in immunology · 2025
    Review
  10. Lifestyle and dietary interventions for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Review
  11. Positive pressure therapy for Ménière's disease.The Cochrane database of systematic reviews · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Histopathology of Meniere's disease.Operative techniques in otolaryngology--head and neck surgery · 2016
    Article
  18. Motion Sickness: Current Knowledge and Recent Advance.CNS neuroscience & therapeutics · 2016
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giuseppe ChiarellaDepartment of experimental and Clinical Medicine, Audiology and Phoniatrics Unit, Magna Graecia University of Catanzaro, Catanzaro, Italy.
C PetroloDepartment of experimental and Clinical Medicine, Audiology and Phoniatrics Unit, Magna Graecia University of Catanzaro, Catanzaro, Italy.
E CassandroDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our understanding of the genetic basis of Ménière's disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease.

Indexed as

etiologygeneMènière’s diseasepathogenesisvertigo

Identifiers

PMID25609993
PMCPMC4293923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.