Trial reportInternational journal of chronic obstructive pulmonary disease2015
Symptoms and impact of COPD assessed by an electronic diary in patients with moderate-to-severe COPD: psychometric results from the SHINE study.
Trial report in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Compliance With Mobile Ecological Momentary Assessment of Self-Reported Health-Related Behaviors and Psychological Constructs in Adults: Systematic Review and Meta-analysis.Journal of medical Internet research · 2021Pooled it
- Daytime symptoms of chronic obstructive pulmonary disease: a systematic review.NPJ primary care respiratory medicine · 2020Pooled it
- Association between morning symptoms and physical activity in COPD: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2017Pooled it
- Impact of baseline symptoms and health status on COPD exacerbations in the FLAME study.Respiratory research · 2020Trial
- Capturing Exacerbations of Chronic Obstructive Pulmonary Disease with EXACT. A Subanalysis of FLAME.American journal of respiratory and critical care medicine · 2019Trial
- Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING).International journal of chronic obstructive pulmonary disease · 2016Trial
- Association of daily lung condition in COPD patients with wearable speech and physiological data.Scientific reports · 2025Article
- Use of Ecological Momentary Assessment to Measure Dyspnea in COPD.International journal of chronic obstructive pulmonary disease · 2024Article
- Clinical implications of wheezing in patients with chronic obstructive pulmonary disease.Journal of thoracic disease · 2023Article
- Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology.Respirology (Carlton, Vic.) · 2022Article
- Longitudinal investigation of the factor structure of the Parkinson's disease activities of daily living, interference and dependence instrument.Frontiers in neurology · 2022Article
- Treatment Preferences of Patients with Chronic Obstructive Pulmonary Disease: Results from Qualitative Interviews and Focus Groups in the United Kingdom, United States, and Germany.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021Article
- Indacaterol/glycopyrronium versus tiotropium or glycopyrronium in long-acting bronchodilator-naïve COPD patients: A pooled analysis.Respirology (Carlton, Vic.) · 2020Article
- Preferences for Use and Design of Electronic Patient-Reported Outcomes in Patients with Chronic Obstructive Pulmonary Disease.The patient · 2019Article
- Degree of control of patients with chronic obstructive pulmonary disease in Spain: SINCON study.BMC pulmonary medicine · 2018Article
- Evaluating the Impact and Benefits of Fluticasone Furoate/Vilanterol in Individuals with Asthma or COPD: A Mixed-Methods Analysis of Patient Experiences.Advances in therapy · 2018Article
- Can Geriatric Psychiatry Patients Complete Symptoms Self-Reports Using Tablets? A Randomized Study.Canadian geriatrics journal : CGJ · 2017Article
- Life Impact and Treatment Preferences of Individuals with Asthma and Chronic Obstructive Pulmonary Disease: Results from Qualitative Interviews and Focus Groups.Advances in therapy · 2017Article
- Wheezing, a significant clinical phenotype of COPD: experience from the Taiwan Obstructive Lung Disease Study.International journal of chronic obstructive pulmonary disease · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptoms, particularly dyspnea, and activity limitation, have an impact on the health status and the ability to function normally in patients with chronic obstructive pulmonary disease (COPD).
methodsTo develop an electronic patient diary (eDiary), qualitative patient interviews were conducted from 2009 to 2010 to identify relevant symptoms and degree of bother due to symptoms. The eDiary was completed by a subset of 209 patients with moderate-to-severe COPD in the 26-week QVA149 SHINE study. Two morning assessments (since awakening and since the last assessment) and one evening assessment were made each day. Assessments covered five symptoms ("shortness of breath," "phlegm/mucus," "chest tightness," "wheezing," and "coughing") and two impact items ("bothered by COPD" and "difficulty with activities") and were scored on a 10-point numeric scale.
resultsPatient compliance with the eDiary was 90.4% at baseline and 81.3% at week 26. Correlations between shortness of breath and impact items were >0.95. Regression analysis showed that shortness of breath was a highly significant (P<0.0001) predictor of impact items. Exploratory factor analysis gave a single factor comprising all eDiary items, including both symptoms and impact items. Shortness of breath, the total score (including five symptoms and two impact items), and the five-item symptom score from the eDiary performed well, with good consistency and reliability. The eDiary showed good sensitivity to change, with a 0.6 points reduction in the symptoms scores (on a 0-10 point scale) representing a meaningful change.
conclusionThe eDiary was found to be valid, reliable, and responsive. The high correlations obtained between "shortness of breath" and the ratings of "bother" and "difficulty with activities" confirmed the relevance of this symptom in patients with COPD. Future studies will be required to explore further psychometric properties and their ability to differentiate between COPD treatments.
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