Evidence map›Paper›PMID 25609935›Full record

Trial reportClinical interventions in aging2015

Comparison of strength training, aerobic training, and additional physical therapy as supplementary treatments for Parkinson's disease: pilot study.

Alessandro Carvalho, Dannyel Barbirato, Narahyana Araujo, Jose Vicente Martins, Jose Luiz Sá Cavalcanti, Tony Meireles Santos, Evandro S Coutinho, Jerson Laks, Andrea C Deslandes

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 16 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02600052 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Efficacy of Pattern Respiratory Proprioceptive Neuromuscular Facilitation Associated With Aerobic Training on the Volumes, Lung Capacity and Six-minute Walking Test in Individuals With Parkinson: Randomized Clinical Trial

TypeinterventionalSponsorUniversidade Federal de PernambucoRan2016 to 2017Enrolled30ConditionsParkinson DiseaseArmsPNF, treadmill
NCT07618728 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility and Preliminary Effectiveness of an Individualised Multimodal Group-Based Exercise Programme for People With Parkinson's Disease: A Non-Randomized Feasibility Study

TypeinterventionalSponsorUniversidad Rey Juan CarlosRan2025 to 2027Enrolled64ConditionsPARKINSON DISEASE (Disorder)ArmsExercise Group
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 16 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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  13. Current Perspectives on Aerobic Exercise in People with Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alessandro CarvalhoCentro de Doença de Alzheimer e Outros Transtornos da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil ; Centro de Estudo e Pesquisa do Envelhecimento, Instituto Vital Brazil, Rio de Janeiro, Brazil.
Dannyel BarbiratoCentro de Doença de Alzheimer e Outros Transtornos da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Narahyana AraujoCentro de Doença de Alzheimer e Outros Transtornos da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Jose Vicente MartinsInstituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Jose Luiz Sá CavalcantiInstituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Tony Meireles SantosDepartamento de Educação Física da Universidade Federal de Pernambuco, Pernambuco, Brazil.
Evandro S CoutinhoDepartamento de Epidemiologia e Métodos Quantitativos em saúde. Escola Nacional de Saúde Pública-FIOCRUZ, Rio de Janeiro, Brazil.
Jerson LaksCentro de Doença de Alzheimer e Outros Transtornos da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil ; Centro de Estudo e Pesquisa do Envelhecimento, Instituto Vital Brazil, Rio de Janeiro, Brazil.
Andrea C DeslandesCentro de Doença de Alzheimer e Outros Transtornos da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhysical rehabilitation is commonly used in patients with Parkinson's disease (PD) to improve their health and alleviate the symptoms.

objectiveWe compared the effects of three programs, strength training (ST), aerobic training (AT), and physiotherapy, on motor symptoms, functional capacity, and electroencephalographic (EEG) activity in PD patients.

methodsTwenty-two patients were recruited and randomized into three groups: AT (70% of maximum heart rate), ST (80% of one repetition maximum), and physiotherapy (in groups). Subjects participated in their respective interventions twice a week for 12 weeks. The assessments included measures of disease symptoms (Unified Parkinson's Disease Rating Scale [UPDRS]), functional capacity (Senior Fitness Test), and EEG before and after 12 weeks of intervention.

resultsThe PD motor symptoms (UPDRS-III) in the group of patients who performed ST and AT improved by 27.5% (effect size [ES]=1.25, confidence interval [CI]=-0.11, 2.25) and 35% (ES=1.34, CI=-0.16, 2.58), respectively, in contrast to the physiotherapy group, which showed a 2.9% improvement (ES=0.07, CI=-0.85, 0.99). Furthermore, the functional capacity of all three groups improved after the intervention. The mean frequency of the EEG analysis mainly showed the effect of the interventions on the groups (F=11.50, P=0.0001).

conclusionST and AT in patients with PD are associated with improved outcomes in disease symptoms and functional capacity.

Indexed as

Physical Therapy ModalitiesQuality of LifeActivities of Daily LivingAgedElectroencephalographyExerciseFemaleGaitHumansMaleMiddle AgedParkinson DiseasePilot ProjectsResistance TrainingSeverity of Illness IndexTreatment Outcomefunctional capacityParkinson’s diseasephysical exercisephysical therapyquality of life

Identifiers

PMID25609935
PMCPMC4293290
OpenAlexW2038957912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.