ArticleScientific reports2015
Transmission of tularemia from a water source by transstadial maintenance in a mosquito vector.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A need for null models in understanding disease transmission: the example of Mycobacterium ulcerans (Buruli ulcer disease).FEMS microbiology reviews · 2022Pooled it
- First molecular detection ofVeterinary and animal science · 2025Article
- Virulence and genome analysis of three historicalFrontiers in cellular and infection microbiology · 2025Article
- Modeling the differential effect of prescribed fire on multi-vector tick-borne tularemia disease.PloS one · 2025Article
- Article
- Mosquito Vectors (Diptera:Insects · 2022Review
- Midguts of Culex pipiens L. (Diptera: Culicidae) as a potential source of raw milk contamination with pathogens.Scientific reports · 2022Article
- Why vary what's working? Phase variation and biofilm formation inFrontiers in microbiology · 2022Review
- Aptamers isolated against mosquito-borne pathogens.World journal of microbiology & biotechnology · 2021Review
- Long-Term Survival of Virulent Tularemia Pathogens outside a Host in Conditions That Mimic Natural Aquatic Environments.Applied and environmental microbiology · 2021Article
- Tularemia as a Mosquito-Borne Disease.Microorganisms · 2020Review
- Ecology ofAnnual review of entomology · 2020Review
- Francisella novicida and F. philomiragia biofilm features conditionning fitness in spring water and in presence of antibiotics.PloS one · 2020Article
- CRISPR/Cas9-mediated gene deletion of the ompA gene in symbiotic Cedecea neteri impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes.PLoS neglected tropical diseases · 2019Article
- Lymph node abscess caused by Francisella tularensis - a rare differential diagnosis for cervical lymph node swelling: a case report.Journal of medical case reports · 2019Article
- Tularemia as a waterborne disease: a review.Emerging microbes & infections · 2019Review
- Insects and the Transmission of Bacterial Agents.Microbiology spectrum · 2018Review
- Detection of malaria sporozoites expelled during mosquito sugar feeding.Scientific reports · 2018Article
- A Single Mechanosensitive Channel Protects Francisella tularensis subsp. holarctica from Hypoosmotic Shock and Promotes Survival in the Aquatic Environment.Applied and environmental microbiology · 2018Article
- Serological evidence ofNew microbes and new infections · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes are thought to function as mechanical vectors of Francisella tularensis subspecies holarctica (F. t. holarctica) causing tularemia in humans. We investigated the clinical relevance of transstadially maintained F. t. holarctica in mosquitoes. Aedes egypti larvae exposed to a fully virulent F. t. holarctica strain for 24 hours, were allowed to develop into adults when they were individually homogenized. Approximately 24% of the homogenates tested positive for F. t. DNA in PCR. Mice injected with the mosquito homogenates acquired tularemia within 5 days. This novel finding demonstrates the possibility of transmission of bacteria by adult mosquitoes having acquired the pathogen from their aquatic larval habitats.
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