ArticleScientific reports2015
3D-DIP-Chip: a microarray-based method to measure genomic DNA damage.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Transcriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drugs.bioRxiv : the preprint server for biology · 2025Article
- Chromatin accessibility changes at intergenic regions are associated with ovarian cancer drug resistance.Clinical epigenetics · 2021Article
- Genomic Characterization of Cisplatin Response Uncovers Priming of Cisplatin-Induced Genes in a Resistant Cell Line.International journal of molecular sciences · 2021Article
- Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes.International journal of molecular sciences · 2019Article
- Genome-wide mapping of nucleotide excision repair with XR-seq.Nature protocols · 2019Article
- Nucleosome remodeling at origins of global genome-nucleotide excision repair occurs at the boundaries of higher-order chromatin structure.Genome research · 2019Article
- ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma.Nature communications · 2018Article
- Dynamic maps of UV damage formation and repair for the human genome.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- UV-Induced DNA Damage and Mutagenesis in Chromatin.Photochemistry and photobiology · 2017Review
- The Cartography of UV-induced DNA Damage Formation and DNA Repair.Photochemistry and photobiology · 2017Review
- Base-Resolution Analysis of Cisplatin-DNA Adducts at the Genome Scale.Angewandte Chemie (International ed. in English) · 2016Article
- Emerging roles for histone modifications in DNA excision repair.FEMS yeast research · 2016Review
- Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin.Genome research · 2016Article
- Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Genomic approaches to DNA repair and mutagenesis.DNA repair · 2015Review
- Chromatin dynamics after DNA damage: The legacy of the access-repair-restore model.DNA repair · 2015Review
- Transcription Blockage Leads to New Beginnings.Biomolecules · 2015Review
- Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution.Genes & development · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Genotoxins cause DNA damage, which can result in genomic instability. The genetic changes induced have far-reaching consequences, often leading to diseases such as cancer. A wide range of genotoxins exists, including radiations and chemicals found naturally in the environment, and in man-made forms created by human activity across a variety of industries. Genomic technologies offer the possibility of unravelling the mechanisms of genotoxicity, including the repair of genetic damage, enhancing our ability to develop, test and safely use existing and novel materials. We have developed 3D-DIP-Chip, a microarray-based method to measure the prevalence of genomic genotoxin-induced DNA damage. We demonstrate the measurement of both physical and chemical induced DNA damage spectra, integrating the analysis of these with the associated changes in histone acetylation induced in the epigenome. We discuss the application of the method in the context of basic and translational sciences.
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Registered trials
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