ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Synaptic consolidation: from synapses to behavioral modeling.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Polyhexamethylene guanidine phosphate exposure induces abnormal behaviors by disrupting synaptic formation and activity in the cerebral cortex.Journal of neuroinflammation · 2026Article
- Dual-montage high-definition transcranial direct current stimulation (HD-tDCS) modulates the neural dynamics serving working memory.NeuroImage · 2025Article
- Continual deep reinforcement learning with task-agnostic policy distillation.Scientific reports · 2024Article
- Competitive processes shape multi-synapse plasticity along dendritic segments.Nature communications · 2024Article
- Learning with filopodia and spines: Complementary strong and weak competition lead to specialized, graded, and protected receptive fields.PLoS computational biology · 2024Article
- Attractor neural networks with double well synapses.PLoS computational biology · 2024Article
- Neurobiological Causal Models of Language Processing.Neurobiology of language (Cambridge, Mass.) · 2024Article
- Neuromodulator-dependent synaptic tagging and capture retroactively controls neural coding in spiking neural networks.Scientific reports · 2022Article
- Long-term memory, synaptic plasticity and dopamine in rodent medial prefrontal cortex: Role in executive functions.Frontiers in behavioral neuroscience · 2022Review
- Analysis of personality traits and academic performance in higher education at a Colombian university.Heliyon · 2021Article
- Energetics of stochastic BCM type synaptic plasticity and storing of accurate information.Journal of computational neuroscience · 2021Article
- Memory consolidation and improvement by synaptic tagging and capture in recurrent neural networks.Communications biology · 2021Article
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- Optimal Stimulation Protocol in a Bistable Synaptic Consolidation Model.Frontiers in computational neuroscience · 2019Article
- Intrinsic Spine Dynamics Are Critical for Recurrent Network Learning in Models With and Without Autism Spectrum Disorder.Frontiers in computational neuroscience · 2019Article
- Eligibility Traces and Plasticity on Behavioral Time Scales: Experimental Support of NeoHebbian Three-Factor Learning Rules.Frontiers in neural circuits · 2018Review
- The computational nature of memory modification.eLife · 2017Article
- Hebbian plasticity requires compensatory processes on multiple timescales.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synaptic plasticity, a key process for memory formation, manifests itself across different time scales ranging from a few seconds for plasticity induction up to hours or even years for consolidation and memory retention. We developed a three-layered model of synaptic consolidation that accounts for data across a large range of experimental conditions. Consolidation occurs in the model through the interaction of the synaptic efficacy with a scaffolding variable by a read-write process mediated by a tagging-related variable. Plasticity-inducing stimuli modify the efficacy, but the state of tag and scaffold can only change if a write protection mechanism is overcome. Our model makes a link from depotentiation protocols in vitro to behavioral results regarding the influence of novelty on inhibitory avoidance memory in rats.
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