ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Audition-independent vocal crystallization associated with intrinsic developmental gene expression dynamics.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Neural activation in a septal area is related to intrinsic motivation for non-courtship singing in adult zebra finches.Scientific reports · 2025Article
- Expansion of learning capacity elicited by interspecific hybridization.Science advances · 2024Article
- Daily singing of adult songbirds functions to maintain song performance independently of auditory feedback and age.Communications biology · 2024Article
- A predisposed motor bias shapes individuality in vocal learning.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Article
- Measuring context dependency in birdsong using artificial neural networks.PLoS computational biology · 2021Article
- Resurgent NaNature communications · 2021Article
- Intrinsic motivation for singing in songbirds is enhanced by temporary singing suppression and regulated by dopamine.Scientific reports · 2021Article
- Gene manipulation to test links between genome, brain and behavior in developing songbirds: a test case.The Journal of experimental biology · 2020Review
- Inhibitory cell populations depend on age, sex, and prior experience across a neural network for Critical Period learning.Scientific reports · 2019Article
- Transcriptional regulatory divergence underpinning species-specific learned vocalization in songbirds.PLoS biology · 2019Article
- Exploring the molecular basis of neuronal excitability in a vocal learner.BMC genomics · 2019Article
- Vocal practice regulates singing activity-dependent genes underlying age-independent vocal learning in songbirds.PLoS biology · 2018Article
- Neuroestrogens rapidly shape auditory circuits to support communication learning and perception: Evidence from songbirds.Hormones and behavior · 2018Review
- Singing activity-driven Arc expression associated with vocal acoustic plasticity in juvenile songbird.The European journal of neuroscience · 2018Article
- Recurrent development of song idiosyncrasy without auditory inputs in the canary, an open-ended vocal learner.Scientific reports · 2018Article
- Epigenetic regulation of transcriptional plasticity associated with developmental song learning.Proceedings. Biological sciences · 2018Article
- Sex Differences in Brain Thyroid Hormone Levels during Early Post-Hatching Development in Zebra Finch (Taeniopygia guttata).PloS one · 2017Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complex learned behavior is influenced throughout development by both genetic and environmental factors. Birdsong, like human speech, is a complex vocal behavior acquired through sensorimotor learning and is based on coordinated auditory input and vocal output to mimic tutor song. Song is primarily learned during a specific developmental stage called the critical period. Although auditory input is crucial for acquiring complex vocal patterns, its exact role in neural circuit maturation for vocal learning and production is not well understood. Using audition-deprived songbirds, we examined whether auditory experience affects developmental gene expression in the major elements of neural circuits that mediate vocal learning and production. Compared with intact zebra finches, early-deafened zebra finches showed excessively delayed vocal development, but their songs eventually crystallized. In contrast to the different rates of song development between the intact and deafened birds, developmental gene expression in the motor circuit is conserved in an age-dependent manner from the juvenile stage until the older adult stage, even in the deafened birds, which indicates the audition-independent robustness of gene expression dynamics during development. Furthermore, even after adult deafening, which degrades crystallized song, the deteriorated songs ultimately restabilized at the same point when the early-deafened birds stabilized their songs. These results indicate a genetic program-associated inevitable termination of vocal plasticity that results in audition-independent vocal crystallization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.