Evidence map›Paper›PMID 25609546›Full record

Trial reportInternational urology and nephrology2015

The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury.

Guoqing Chen, Limin Liao, Yao Li

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04074616 nacompletednot on this mapstarted 2019, after this paper: background citation

Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2019 to 2023Enrolled50ConditionsChronic Spinal Cord Injury, Neurogenic BladderArmsHigh Dose, Low dose
NCT04350359 nacompletednot on this mapstarted 2020, after this paper: background citation

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2020 to 2026Enrolled111ConditionsSpinal Cord InjuriesArmsVariable-dose TTNS Protocol 5 x week, Fixed-dose TTNS Protocol, Variable-dose TTNS Protocol 2 x week
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  14. Narrative review of current neuromodulation modalities for spinal cord injury.Frontiers in pain research (Lausanne, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Guoqing ChenDepartment of Urology, China Rehabilitation Research Center, Beijing, 100068, China.
Limin Liao
Yao Li
Capital Medical University · CNCapital University · USChongqing Institute of Green and Intelligent Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using adhesive skin surface electrodes versus solifenacin succinate (SS) in patients with neurogenic detrusor overactivity (NDO) secondary to spinal cord injury (SCI).

methodsA randomized controlled study involving 100 patients with NDO secondary to SCI was conducted. Patients were randomized into two groups. In group A, patients received PTNS using adhesive skin surface electrodes for 4 weeks. In group B, patients underwent SS treatment for 4 weeks. Bladder diaries and incontinence quality of life questionnaire were reviewed before treatment and 2 and 4 weeks after treatment.

resultsImprovement in all bladder diary parameters was statistically significant within each group 2 and 4 weeks after treatment compared to baseline (p < 0.05), but did not reach statistical significance between the PTNS and SS groups (p > 0.05). Compared to SS, PTNS was not associated with any unanticipated adverse events.

conclusionsPTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI. This therapy is not only no difference comparing to SS therapy but also noninvasive and easily managed by patients.

Indexed as

Tibial NerveTranscutaneous Electric Nerve StimulationAdultCervical VertebraeElectrodesFemaleHumansLumbar VertebraeMaleMuscarinic AntagonistsQuality of LifeSolifenacin SuccinateSpinal Cord InjuriesSurveys and QuestionnairesThoracic VertebraeTreatment OutcomeMuscarinic AntagonistsSolifenacin Succinate

Identifiers

PMID25609546
OpenAlexW2000315776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.