Trial reportClinical oral investigations2015
Clinical evaluation of the efficacy of one self-adhesive composite in dental hypersensitivity.
Trial report in Clinical oral investigations, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparative Study of a Self-adhering Material in Dental Hypersensitivity in Xerostomic Patients Due to Radiotherapy
Long-term Response of Three Biomaterials Used as Desensitizer Agents Under Oral Environmental Exposure.
Randomized Clinical Trial to Evaluate the Efficacy of Nano-hydroxyapatite Combined With the Potassium Nitrate for the Treatment of Dental Sensitivity
Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Effect of 940 nm laser diode irradiation prior to bonding procedure on postoperative sensitivity following class II composite restorations: a split-mouth randomized clinical trial.Lasers in medical science · 2021Trial
- Efficiency of desensitizing materials in xerostomic patients with head and neck cancer: a comparative clinical study.Clinical oral investigations · 2020Trial
- Evaluation of postoperative sensitivity in restorations with self-adhesive resin: a randomized split-mouth design controlled study.Clinical oral investigations · 2020Trial
- Reducing dentine hypersensitivity with nano-hydroxyapatite toothpaste: a double-blind randomized controlled trial.Clinical oral investigations · 2018Trial
- Effectiveness on oral pain of 808-nm diode laser used prior to composite restoration for symptomatic non-carious cervical lesions unresponsive to desensitizing agents.Lasers in medical science · 2017Trial
- Self-Adhesive Flowable Resin Composites-Are We Going Somewhere?Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Review
- The Impact of Calcination on the Structure, Bioactivity, and Biocompatibility of Sol-Gel-Derived Glasses.ACS omega · 2025Article
- Clinical Performance of Self-Adhesive vs. Conventional Flowable Resin Composite Restorations in Posterior Teeth: A Systematic Review and Meta-Analysis of Randomized Trials.Journal of clinical medicine · 2025Review
- Effectiveness of Calcium Phosphate Desensitising Agents in Dental Hypersensitivity Over 24 Weeks of Clinical Evaluation.Nanomaterials (Basel, Switzerland) · 2019Article
- Polymer-Based Direct Filling Materials.Dental clinics of North America · 2017Review
- Catechol-Functionalized Synthetic Polymer as a Dental Adhesive to Contaminated Dentin Surface for a Composite Restoration.Biomacromolecules · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of the present study was to investigate the clinical effectiveness over 12 weeks of Vertise Flow(™), a self-adhering composite, in dental hypersensitivity (DH). MATERIAL AND
methodsThe study was conducted as a split-mouth randomized clinical trial. Vertise Flow™ was compared to the following: (1) Universal Dentine Sealant, (2) Clearfil Protect Bond, and (3) Flor-Opal® Varnish. A total of 46 patients with 116 hypersensitive teeth were studied. Pain experience was generated by a cold stimulus and assessed using the visual analog scale (VAS) of pain. The response was recorded before the application of the materials (pre-1), immediately after (post-1), at 1- (post-2), 2- (post-3), and 12-week controls (post-4). Statistical differences in VAS were performed using the Kruskal-Wallis analysis at the different time-points (P < 0.05), adjusting statistical significances for multiple comparisons (Bonferroni correction).
resultsAll the materials showed any statistically significant differences at the baseline. After the application of each material, a VAS decrease was demonstrated at every post-control. VF showed significant hypersensitivity reduction in post-1. Statistically significant relief was also observed in post-2 while no significant differences were detected in post-3 and post-4.
conclusionsAfter 12-week controls, there was no statistically significant hypersensitivity reduction using VF in respect to the other materials. On the other hand, any significant differences were detected in the decrease of the VAS irrespective of the desensitizing agent employed at the 12-week controls. CLINICAL RELEVANCE: The significant increase in VAS scores within the 12-weeks of environment suggested there is instability of VF when used as desensitizing agent.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.