Evidence map›Paper›PMID 25609032›Full record

Trial reportClinical oral investigations2015

Clinical evaluation of the efficacy of one self-adhesive composite in dental hypersensitivity.

R Pinna, A Bortone, G Sotgiu, S Dore, P Usai, E Milia

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02766127 nacompletednot on this map

A Comparative Study of a Self-adhering Material in Dental Hypersensitivity in Xerostomic Patients Due to Radiotherapy

TypeinterventionalSponsorUniversità degli Studi di SassariRan2012 to 2015Enrolled17ConditionsDentin Sensitivity, XerostomiaArmsVeritise Flow, Universal Dentin Sealant, Clearfil Protect Bond, Flor-Opal® Varnish
NCT02770573 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Long-term Response of Three Biomaterials Used as Desensitizer Agents Under Oral Environmental Exposure.

TypeinterventionalSponsorUniversità degli Studi di SassariRan2016 to 2017Enrolled90ConditionsDentin SensitivityArmsCavex Bite&White ExSense, Kuraray Teethmate™ Desensitizer, Ghimas Dentin Desensitizer
NCT02895321 phase4completednot on this mapstarted 2016, after this paper: background citation

Randomized Clinical Trial to Evaluate the Efficacy of Nano-hydroxyapatite Combined With the Potassium Nitrate for the Treatment of Dental Sensitivity

TypeinterventionalSponsorUniversità degli Studi di SassariRan2016 to 2016Enrolled35ConditionsDentin SensitivityArmsCavex Bite&White ExSense, Colgate, Protection Caries, Placebo gel
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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  5. Trial
  6. Self-Adhesive Flowable Resin Composites-Are We Going Somewhere?Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Polymer-Based Direct Filling Materials.Dental clinics of North America · 2017
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R PinnaDepartment of Biomedical Sciences, University of Sassari, Viale San Pietro, 43/c, 07100, Sassari, Italy.
A Bortone
G Sotgiu
S Dore
P Usai
E Milia
University of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the present study was to investigate the clinical effectiveness over 12 weeks of Vertise Flow(™), a self-adhering composite, in dental hypersensitivity (DH). MATERIAL AND

methodsThe study was conducted as a split-mouth randomized clinical trial. Vertise Flow™ was compared to the following: (1) Universal Dentine Sealant, (2) Clearfil Protect Bond, and (3) Flor-Opal® Varnish. A total of 46 patients with 116 hypersensitive teeth were studied. Pain experience was generated by a cold stimulus and assessed using the visual analog scale (VAS) of pain. The response was recorded before the application of the materials (pre-1), immediately after (post-1), at 1- (post-2), 2- (post-3), and 12-week controls (post-4). Statistical differences in VAS were performed using the Kruskal-Wallis analysis at the different time-points (P < 0.05), adjusting statistical significances for multiple comparisons (Bonferroni correction).

resultsAll the materials showed any statistically significant differences at the baseline. After the application of each material, a VAS decrease was demonstrated at every post-control. VF showed significant hypersensitivity reduction in post-1. Statistically significant relief was also observed in post-2 while no significant differences were detected in post-3 and post-4.

conclusionsAfter 12-week controls, there was no statistically significant hypersensitivity reduction using VF in respect to the other materials. On the other hand, any significant differences were detected in the decrease of the VAS irrespective of the desensitizing agent employed at the 12-week controls. CLINICAL RELEVANCE: The significant increase in VAS scores within the 12-weeks of environment suggested there is instability of VF when used as desensitizing agent.

Indexed as

Dental CementsDentin SensitivityFemaleHumansMaleTreatment OutcomeDental Cements

Identifiers

PMID25609032
OpenAlexW2046455843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.