Evidence map›Paper›PMID 25608648›Full record

ArticleBMC health services research2015

Economic burden of illness associated with diabetic foot ulcers in Canada.

Robert B Hopkins, Natasha Burke, John Harlock, Jathishinie Jegathisawaran, Ron Goeree

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 42 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 6 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03370237 completednot on this mapstarted 2017, after this paper: background citation

Reliability of a Diabetic Foot Ulcer Risk Stratification and Referral Algorithm

TypeobservationalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2017 to 2017Enrolled51ConditionsFoot Ulcer, Diabetic
NCT03506776 nacompletednot on this mapstarted 2017, after this paper: background citation

Foot Intervention Study Utilizing Commercially Available Infrared Thermometers With Individuals With Diabetes Using a Mixed Methods Approach

TypeinterventionalSponsorMemorial University of NewfoundlandRan2017 to 2019Enrolled62ConditionsDiabetic FootArmsEducation and Thermometer Group, Education Only Group
NCT06092827 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Feasibility and Acceptability Study of a Non Weight-bearing Physical Activity Program for People With Diabetic Foot Ulceration (DB ACTIV)

TypeinterventionalSponsorUniversité du Québec à Trois-RivièresRan2023 to 2025Enrolled12ConditionsDiabetic Foot, Cardiopulmonary, Physical InactivityArmsNon weight-bearing physical activity program
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 6 syntheses or guidelines pooled it, 118 citations in OpenAlex.

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  7. Article
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  9. Reducing Hospitalisations With a Skin and Soft Tissue Infection Clinic.Journal of evaluation in clinical practice · 2025
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  11. Cost-Effectiveness of FreeStyle Libre for Glucose Self-Management Among People with Diabetes Mellitus: A Canadian Private Payer Perspective.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Robert B HopkinsPrograms for Assessment of Technology in Health (PATH) Research Institute, St. Joseph's Healthcare Hamilton, Suite 2000 (20th floor), 25 Main St West, Hamilton, ON, Canada. hopkinr@mcmaster.ca.
Natasha BurkePrograms for Assessment of Technology in Health (PATH) Research Institute, St. Joseph's Healthcare Hamilton, Suite 2000 (20th floor), 25 Main St West, Hamilton, ON, Canada. nburke@mcmaster.ca.
John HarlockDivision of Vascular Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. harlocj@mcmaster.ca.
Jathishinie JegathisawaranPrograms for Assessment of Technology in Health (PATH) Research Institute, St. Joseph's Healthcare Hamilton, Suite 2000 (20th floor), 25 Main St West, Hamilton, ON, Canada. jjegath@mcmaster.ca.
Ron GoereePrograms for Assessment of Technology in Health (PATH) Research Institute, St. Joseph's Healthcare Hamilton, Suite 2000 (20th floor), 25 Main St West, Hamilton, ON, Canada. goereer@mcmaster.ca.
Programs for Assessment of Technology in Health Research Institute · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary objective was to estimate the national burden of illness in Canada for diabetic foot ulcer (DFU) for 2011. Secondary objectives included estimating the national incidence and prevalence of DFU, and the 3-year average cost for DFU incident cases.

methodsAnalyses were conducted using four national databases for the period April 1, 2006 to March 31, 2011, with cases being identified by ICD-10 CA codes. Resource utilization and costs, expressed in 2011 Canadian dollars, were estimated for DFU-related hospitalizations, emergency care (ER), same day surgeries, home care, long term care, physician visits and caregiver time losses.

resultsIn Canada in the year 2011, DFU was associated with 16,883 hospital admissions (327,140 days), 31,095 ER or clinic visits, 41,367 rehabilitation clinic visits, and 26,493 interventions, including 6,036 amputations and 5,796 surgical debridements. This acute institution care represented $320.5 M, and with an additional $125.4 M for home care and $63.1 M for long term care, the annual cost associated with DFU-related care was $547.0 M, or $21,371 annual cost per prevalent case. In 2011, the national prevalence of DFU was 25,597 cases (75.1 per 100,000 population), consisting of 16,161 men (63.1%) and 9,436 women (36.9%), and an estimated 14,449 incident cases. For an incident case of DFU, the average 3-year cumulative cost was $52,360.

conclusionThe annual burden for DFU cases that have at least one admission or ER/clinic visit over a 5 year period is higher than previously reported.

Indexed as

Cost of IllnessAgedAmputation, SurgicalCanadaDiabetic FootEpidemiologic MethodsFemaleHealth ResourcesHome Care ServicesHospitalizationHumansInternational Classification of DiseasesLong-Term CareMale

Identifiers

PMID25608648
PMCPMC4307900
OpenAlexW1998010112

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.