Evidence map›Paper›PMID 25608520›Full record

Trial reportNeurorehabilitation and neural repair2015

The Effects of Highly Challenging Balance Training in Elderly With Parkinson's Disease: A Randomized Controlled Trial.

David Conradsson, Niklas Löfgren, Håkan Nero, Maria Hagströmer, Agneta Ståhle, Johan Lökk, Erika Franzén

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 87 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02727478 nacompletednot on this mapstarted 2016, after this paper: background citation

Highly Challenging Balance Training for People With Parkinson's Disease (the BETA-PD Study): Non-randomized Hybrid Effectiveness-implementation Trial

TypeinterventionalSponsorKarolinska InstitutetRan2016 to 2018Enrolled117ConditionsParkinson DiseaseArmsHiBalance training program
NCT03213873 nacompletednot on this mapstarted 2017, after this paper: background citation

Effects of the HiBalance-program: Linking Clinical Signs and Symptoms to Changes in the Brain in People With Parkinson´s Disease

TypeinterventionalSponsorKarolinska InstitutetRan2017 to 2019Enrolled95ConditionsParkinson Disease, Physical Activity, Gait Disorders, Neurologic, Neural DegenerationArmsHiBalance, Speech and communication therapy
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David ConradssonKarolinska Institutet, Stockholm, Sweden Karolinska University Hospital, Stockholm, Sweden David.Conradsson.1@ki.se Erika.Franzen@ki.se.
Niklas LöfgrenKarolinska Institutet, Stockholm, Sweden.
Håkan NeroKarolinska Institutet, Stockholm, Sweden.
Maria HagströmerKarolinska Institutet, Stockholm, Sweden Karolinska University Hospital, Stockholm, Sweden.
Agneta StåhleKarolinska Institutet, Stockholm, Sweden Karolinska University Hospital, Stockholm, Sweden.
Johan LökkKarolinska Institutet, Stockholm, Sweden Karolinska University Hospital, Stockholm, Sweden.
Erika FranzénKarolinska Institutet, Stockholm, Sweden Karolinska University Hospital, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHighly challenging exercises have been suggested to induce neuroplasticity in individuals with Parkinson's disease (PD); however, its effect on clinical outcomes remains largely unknown.

objectiveTo evaluate the short-term effects of the HiBalance program, a highly challenging balance-training regimen that incorporates both dual-tasking and PD-specific balance components, compared with usual care in elderly with mild to moderate PD.

methodsParticipants with PD (n = 100) were randomized, either to the 10-week HiBalance program (n = 51) or to the control group (n = 49). Participants were evaluated before and after the intervention. The main outcomes were balance performance (Mini-BESTest), gait velocity (during normal and dual-task gait), and concerns about falling (Falls Efficacy Scale-International). Performance of a cognitive task while walking, physical activity level (average steps per day), and activities of daily living were secondary outcomes.

resultsA total of 91 participants completed the study. After the intervention, the between group comparison showed significantly improved balance and gait performance in the training group. Moreover, although no significant between group difference was observed regarding gait performance during dual-tasking; the participants in the training group improved their performance of the cognitive task while walking, as compared with the control group. Regarding physical activity levels and activities of daily living, in comparison to the control group, favorable results were found for the training group. No group differences were found for concerns about falling.

conclusionsThe HiBalance program significantly benefited balance and gait abilities when compared with usual care and showed promising transfer effects to everyday living. Long-term follow-up assessments will further explore these effects.

Indexed as

Physical Therapy ModalitiesAccidental FallsAgedAged, 80 and overFemaleGaitHumansMaleParkinson DiseasePostural BalanceTreatment OutcomeWalkingdual taskexercisegaitphysical activitypostural control

Identifiers

PMID25608520
PMCPMC4582836

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.