Evidence map›Paper›PMID 25608449›Full record

ArticleBMC gastroenterology2015

Characteristics and factors related to quality of life in Mexican Mestizo patients with celiac disease.

Karen Lizzete Ramírez-Cervantes, José María Remes-Troche, María Del Pilar Milke-García, Viridiana Romero, Luis F Uscanga

Abstract read
In one paragraph

Article in BMC gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Preference-based measures of health-related quality of life in Indigenous people: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  2. Tools Used to Measure the Physical State of Women with Celiac Disease: A Review with a Systematic Approach.International journal of environmental research and public health · 2020
    Pooled it
  3. Pooled it
  4. Trial
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  10. Review
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  12. Article
  13. Physicians' attitude and perception regarding celiac disease: A questionnaire-based study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2018
    Article
  14. Article
  15. Adherence to gluten-free diet and barriers to adherence in patients with celiac disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2015
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen Lizzete Ramírez-CervantesDepartment of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico. karen_14_89@hotmail.com.
José María Remes-TrocheDigestive Physiology and Gastrointestinal Motility Laboratory, Medical and Biologic Research Institute, Universidad Veracruzana, Veracruz, Mexico. joremes@uv.mx.
María Del Pilar Milke-GarcíaFacultad de Medicina, Miguel Alemán Valdés, Veracruz, Mexico. nutriclinica@hotmail.com.
Viridiana RomeroDepartment of Nutrition Administration, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico. romero61@prodigy.net.mx.
Luis F UscangaDepartment of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico. luis.uscangad@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCeliac disease (CD) is a global health problem and its prevalence is underestimated, especially in Latin American populations. Our aim was to evaluate the clinical features, psychological factors, and health-related quality of life (QoL), before and after diagnosis, in a representative sample of adult Mexican Mestizo patients presenting with CD.

methodsA cross-sectional analysis was conducted on patients seen at two tertiary referral centers in Mexico. QoL before and after CD diagnosis was evaluated using the EuroQoL 5D, the Hospital Anxiety and Depression Scale (HADS), and the disease-specific Celiac Symptom Index (CSI) questionnaires.

resultsWe included 80 patients (80% were women, with a mean age of 48.6 ± 14.1 years). The most common symptoms were diarrhea (86%), bloating (77.5%), and abdominal pain (71.3%). Mean symptom duration was 10.33 ± 6.3 years. Fifty-one patients (63.8%) had a previous diagnosis of irritable bowel syndrome (IBS) and 23 (28.8%) had one of functional dyspepsia. Questionnaire respondents rated their health status at 50% before diagnosis (0 = worst imaginable state, 100 = best imaginable state) and there was a significant improvement of 26% after diagnosis. Thirty-nine percent of the patients had a CSI score > 45 and they were the ones that had been previously diagnosed most often with IBS (p = 0.13) or dyspepsia (p = .036).

conclusionsAt the time of diagnosis, Mexican Mestizo patients with CD had poor QoL. Long-standing symptoms and a previous diagnosis of functional disorders were associated with worse QoL. As in other populations, our results support the need for a detailed examination of cost-effective strategies for increasing CD awareness in clinical practice.

Indexed as

Health StatusQuality of LifeAbdominal PainAdultAgedCeliac DiseaseCross-Sectional StudiesDiarrheaFemaleHumansIndians, North AmericanIrritable Bowel SyndromeMaleMexicoMiddle AgedPsychiatric Status Rating Scales

Identifiers

PMID25608449
PMCPMC4310198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.