Evidence map›Paper›PMID 25606706›Full record

ArticleFuture cardiology2015

A life course approach to cardiovascular aging.

Rebecca Hardy, Debbie A Lawlor, Diana Kuh

Abstract read
In one paragraph

Article in Future cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Chronic mercury exposure and blood pressure in children and adolescents: a systematic review.Environmental science and pollution research international · 2019
    Pooled it
  3. Guideline
  4. Article
  5. Social epidemiology of cardiometabolic risk factors in early adolescents.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rebecca HardyMRC Unit for Lifelong Health & Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK.
Debbie A Lawlor
Diana Kuh

Funding

British Heart Foundation SP/07/008/24066Medical Research Council MC_UU_12013/5Medical Research Council MC_UU_12019/2Medical Research Council MC_UU_12019/4
6 · The paper itself

Abstract

A life course approach in epidemiology investigates the biological, behavioral and social pathways that link physical and social exposures and experiences during gestation, childhood, adolescence and adult life, and across generations, to later-life health and disease risk. We illustrate how a life course approach has been applied to cardiovascular disease, highlighting the evidence in support of the early origins of disease risk. We summarize how trajectories of cardiometabolic risk factors change over the life course and suggest that understanding underlying 'normal' or 'healthy' trajectories and the characteristics that drive deviations from such trajectories offer the potential for early prevention and for identifying means of preventing future disease.

Indexed as

AdolescentAdultAgingBirth WeightBlood GlucoseBlood PressureBody Mass IndexCardiovascular DiseasesChildFemaleHealth Status DisparitiesHumansInfant, NewbornLipidsMenopausePregnancyBlood GlucoseLipidsadipositybirth weightblood pressurecardiovascular diseasecohort studiesglucoselife courselipidslongitudinal modelingsocial inequalities

Identifiers

PMID25606706
PMCPMC4374150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.