ArticleThe British journal of radiology2015
Use of tomotherapy in treatment of synchronous bilateral breast cancer: dosimetric comparison study.
Article in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 26 citations in OpenAlex.
- Hypofractionated and conventionally fractionated radiotherapy for synchronous bilateral breast cancer: clinical and dosimetric outcomes.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Spiral volumetric modulated arc therapy for whole-brain radiotherapy with simultaneous integrated boost to multiple brain metastases.Radiation oncology (London, England) · 2025Article
- Tomotherapy in synchronous and metachronous bilateral breast cancer: Clinical experience.Journal of applied clinical medical physics · 2024Article
- Proton Therapy for Bilateral Breast Cancer Maximizes Normal-Tissue Sparing.International journal of particle therapy · 2023Article
- Adjuvant radiation therapy in breast cancer: Recent advances & Indian data.The Indian journal of medical research · 2021Review
- Evaluation of optimal treatment planning for radiotherapy of synchronous bilateral breast cancer including regional lymph node irradiation.Radiation oncology (London, England) · 2019Article
- Heart and Cardiac Substructure Dose Sparing in Synchronous Bilateral Breast Radiotherapy: A Dosimetric Study of Proton and Photon Radiation Therapy.Frontiers in oncology · 2019Article
- Comparison of Helical Tomotherapy and Direct Tomotherapy in Bilateral Whole Breast Irradiation in a Case of Bilateral Synchronous Grade 1 and Stage 1 Breast Cancer.The American journal of case reports · 2017Article
- First clinical report of helical tomotherapy with simultaneous integrated boost for synchronous bilateral breast cancer.The British journal of radiology · 2017Article
- Synchronous bilateral breast cancer irradiation: clinical and dosimetrical issues using volumetric modulated arc therapy and simultaneous integrated boost.La Radiologia medica · 2017Article
- Article
- Dosimetric Comparision of Coplanar versus Noncoplanar Volumetric Modulated Arc Therapy for Treatment of Bilateral Breast Cancers.Journal of medical physicsArticle
- Comparative Dosimetric Analysis of Three Radiotherapy Fractionation Schedules in Synchronous Bilateral Breast Cancer: Evaluation of Lung and Heart Normal Tissue Complication Probability.Journal of medical physicsArticle
- Evaluation of Optimal Combination of Planning Parameters (Field Width, Pitch, and Modulation Factor) in Helical Tomotherapy for Bilateral Breast Cancer.Journal of medical physicsArticle
- Is Synchronous Bilateral Breast Irradiation Using Flattening Filter-Free Beam-Based Volumetric-Modulated Arc Therapy Beneficial? A Dosimetric Study.Journal of medical physicsArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSynchronous malignancy in both breasts is a rare incidence. The present study aims at dosimetric comparison of conventional bitangential radiotherapy (RT) technique with conventional [field-in-field (FIF)] and rotational [Helical TomoTherapy(®) and TomoDirect™ (TD); Accuray Inc., Sunnyvale, CA] intensity-modulated RT for patients with synchronous bilateral breast cancer (SBBC).
methodsCT data sets of 10 patients with SBBC were selected for the present study. RT was planned for all patients on both sides to whole breast and/or chest wall using the above-mentioned techniques. Six females with breast conservation on at least one side also had a composite plan along with tumour bed (TB) boost using sequential electrons for bitangential and FIF techniques or sequential helical tomotherapy (HT) boost (for TD) or simultaneous integrated boost (SIB) for HT.
resultsAll techniques produced acceptable target coverage. The hotspot was significantly lower with FIF technique and HT but higher with TD. For the organs at risk doses, HT resulted in significant reduction of the higher dose volumes. Similarly, TD resulted in significant reduction of the mean dose to the heart and total lung by reducing the lower dose volumes. All techniques of delivering boost to the TB were comparable in terms of target coverage. HT-SIB markedly reduced mean doses to the total lung and heart by specifically lowering the higher dose volumes.
conclusionThis study demonstrates the cardiac and pulmonary sparing ability of tomotherapy in the setting of SBBC. ADVANCES IN KNOWLEDGE: This is the first study demonstrating feasibility of treatment of SBBC using tomotherapy.
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