ReviewMinerva pediatrica2015
Initial resuscitation and management of pediatric septic shock.
Review in Minerva pediatrica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06720493 (Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Analysis of perioperative corticosteroid therapy in children undergoing cardiac surgery: A systematic review and meta-analysis.Clinical cardiology · 2023Pooled it
- Venoarterial extracorporeal membrane oxygenation as mechanical circulatory support in adult septic shock: a systematic review and meta-analysis with individual participant data meta-regression analysis.Critical care (London, England) · 2021Pooled it
- Pooled it
- Development of a machine-learning risk stratification tool for vasoactive medication need after two-bolus fluid resuscitation in pediatric suspected sepsis.Pediatric research · 2026Article
- Prognostic value of admission ionized calcium for short-term mortality in critically Ill children with sepsis: a single-center retrospective cohort study.Frontiers in pediatrics · 2026Article
- Resource Allocation in the Pediatric Intensive Care Unit in Rwanda.Annals of global health · 2025Article
- Transcriptional markers classifying Escherichia coli and Staphylococcus aureus induced sepsis in adults: A data-driven approach.PloS one · 2024Article
- The Correlations of Human Atrial Natriuretic Peptide on Cardiac Function and Hemodynamics in Pediatric Septic Shock.Open access emergency medicine : OAEM · 2022Article
- Non-invasive Cardiac Output Monitoring and Assessment of Fluid Responsiveness in Children With Shock in the Emergency Department.Frontiers in pediatrics · 2022Article
- Early Prediction of Hemodynamic Shock in Pediatric Intensive Care Units With Deep Learning on Thermal Videos.Frontiers in physiology · 2022Article
- Hemodynamic dysfunction in neonatal sepsis.Pediatric research · 2022Review
- Serum Thrombomodulin to Predict Severity in Pediatric Sepsis-Fancy or Frenzy?Indian journal of pediatrics · 2021Article
- Clinical aspects for differential diagnosis of Kawasaki disease shock syndrome: a case control study.BMC pediatrics · 2021Article
- Improving fluid resuscitation in pediatric shock with LifeFlowOpen access emergency medicine : OAEM · 2019Article
- Fabrication of 6-gingerol, doxorubicin and alginate hydroxyapatite into a bio-compatible formulation: enhanced anti-proliferative effect on breast and liver cancer cells.Chemistry Central journal · 2018Article
- Continuum of care in pediatric sepsis: a prototypical acute care delivery model.Translational pediatrics · 2018Review
- Refractory Shock in Pediatric Emergency Departments: Challenges and Innovations in Early Escalation: A Narrative Review.Sage open pediatricsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The pediatric sepsis syndrome remains a common cause of morbidity, mortality, and health care utilization costs worldwide. The initial resuscitation and management of pediatric sepsis is focused on 1) rapid recognition of abnormal tissue perfusion and restoration of adequate cardiovascular function; 2) eradication of the inciting invasive infection, including prompt administration of empiric broad-spectrum antimicrobial medications; and 3) supportive care of organ system dysfunction. Efforts to improve early and aggressive initial resuscitation and ongoing management strategies have improved outcomes in pediatric severe sepsis and septic shock, though many questions still remain as to the optimal therapeutic strategies for many patients. In this article, we will briefly review the definitions, epidemiology, clinical manifestations, and pathophysiology of sepsis and provide an extensive overview of both current and novel therapeutic strategies used to resuscitate and manage pediatric patients with severe sepsis and septic shock.
Indexed as
Identifiers
25604591PMC4395852What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.