Evidence map›Paper›PMID 25604443›Full record

ReviewThe Plant cell2015

SCFTIR1/AFB-based auxin perception: mechanism and role in plant growth and development.

Mohammad Salehin, Rammyani Bagchi, Mark Estelle

Open access · greenAbstract readReview
In one paragraph

Review in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers.

0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed
71.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

226 citing papers in PubMed, 462 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Auxin Response FactorPlants (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Aux/IAAs: specificity and redundancy.Plant signaling & behavior · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Genome-Wide Identification ofInternational journal of molecular sciences · 2025
    Article

166 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mohammad SalehinHoward Hughes Medical Institute and Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California 92093.
Rammyani BagchiHoward Hughes Medical Institute and Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California 92093.
Mark EstelleHoward Hughes Medical Institute and Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California 92093 mestelle@ucsd.edu.
University of California, San Diego · US

Funding

MOLECULAR GENETICS OF AUXIN ACTION IN ARABIDOPSISR01GM043644 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI ESTELLE, MARK A · 1989 to 2021
$6.0M
Howard Hughes Medical InstituteNIGMS NIH HHS GM43644NIGMS NIH HHS R01 GM043644
6 · The paper itself

Abstract

Auxin regulates a vast array of growth and developmental processes throughout the life cycle of plants. Auxin responses are highly context dependent and can involve changes in cell division, cell expansion, and cell fate. The complexity of the auxin response is illustrated by the recent finding that the auxin-responsive gene set differs significantly between different cell types in the root. Auxin regulation of transcription involves a core pathway consisting of the TIR1/AFB F-box proteins, the Aux/IAA transcriptional repressors, and the ARF transcription factors. Auxin is perceived by a transient coreceptor complex consisting of a TIR1/AFB protein and an Aux/IAA protein. Auxin binding to the coreceptor results in degradation of the Aux/IAAs and derepression of ARF-based transcription. Although the basic outlines of this pathway are now well established, it remains unclear how specificity of the pathway is conferred. However, recent results, focusing on the ways that these three families of proteins interact, are starting to provide important clues.

Indexed as

Gene Expression Regulation, PlantIndoleacetic AcidsPlant Growth RegulatorsPlant ProteinsPlants, Genetically ModifiedIndoleacetic AcidsPlant Growth RegulatorsPlant Proteins

Identifiers

PMID25604443
PMCPMC4330579
OpenAlexW1967452675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.